Sokolovskiĭ V V, Goncharova L L, Kiseleva N N, Makarova I N, Rodionova L P
Vopr Med Khim. 1987 Nov-Dec;33(6):111-3.
Some patterns of the antioxidant system were altered in rat blood and tissues after treatment with noise of 90 dB. Phase alterations were found in content of SH- and SS-groups, in ascorbate-dependent redox balance as well as in activity of glutathione reductase, glucose-6-phosphate- and lactate dehydrogenases. These data suggest that the antioxidant system is of importance in the adaptation reactions. Administration of antioxidant drugs (unitol, ascorbic acid and tocopherol) normalized the antioxidant drugs (unitol, ascorbic acid and tocopherol) normalized the antioxidant system patterns studied. These drugs could be used to enhance the nonspecific body resistance to noise stress.
用90分贝的噪声处理大鼠后,其血液和组织中的一些抗氧化系统模式发生了改变。在SH-和SS-基团的含量、抗坏血酸依赖性氧化还原平衡以及谷胱甘肽还原酶、葡萄糖-6-磷酸脱氢酶和乳酸脱氢酶的活性方面发现了相位改变。这些数据表明抗氧化系统在适应性反应中很重要。给予抗氧化药物(尤尼托尔、抗坏血酸和生育酚)可使所研究的抗氧化系统模式正常化。这些药物可用于增强机体对噪声应激的非特异性抵抗力。