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[Effectiveness of a combined live mumps-measles vaccine].

作者信息

Unanov S S, Korzh Iu N, Dorofeev V M, Iuminova N V, Myshliaeva L A

出版信息

Vopr Virusol. 1987 Nov-Dec;32(6):715-8.

PMID:3445589
Abstract

The reactogenic and areactogenic properties of a live combined mumps-measles vaccine (MMV) prepared in primary cultures of Japanese quail embryo cells from attenuated strains of mumps (L-3) and measles (L-16) viruses were under study. The observations involved 648 infants varying in ages from 1 to 3 years, seronegative to measles and mumps viruses, without the history of the disease and vaccinations against these infections or contraindications to vaccinations. The infants were vaccinated with 5 batches of MMV with different portions of the mumps and measles components. The vaccinees and controls (placebo injections) were observed for 30 days postvaccination. The live MMV was shown to be a safe, well tolerated preparation with low reactogenicity and a high antigenic activity.

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