Kichloo Asim, El-Amir Zain, Dahiya Dushyant Singh, Wani Farah, Shaka Hafeez
Department of Internal Medicine, Central Michigan University College of Medicine , Saginaw , Michigan.
Department of Internal Medicine, Samaritan Medical Center , Watertown , New York.
Proc (Bayl Univ Med Cent). 2021 May 10;34(5):550-554. doi: 10.1080/08998280.2021.1919009. eCollection 2021 Sep.
This study aimed to describe the trends, inpatient outcomes, and disease burden of hospitalizations for ulcerative colitis (UC) and Crohn's disease (CD). Our study included data on hospitalizations with a principal discharge diagnosis of CD and UC gathered from the Nationwide Inpatient Sample for the years 2008, 2010, 2012, 2014, 2016, and 2018. Individuals ≤18 years and elective hospitalizations were excluded. From 2008 to 2018, we noted a rising trend for UC hospitalizations ( trend < 0.001). However, there was no statistically significant trend for CD hospitalizations ( trend = 0.249). The overall inpatient mortality for UC downtrended from 1.09% in 2008 to 0.42% in 2014 ( trend < 0.001). Additionally, inpatient mortality for CD also downtrended with a decrease from 0.28% in 2008 to 0.17% in 2016 ( trend = 0.002). Odds of inpatient mortality from 2008 to 2018 were significantly higher for UC than for CD. In conclusion, both CD and UC saw a significant decline in mortality over the study period, but UC hospitalizations had a higher odds of inpatient mortality for all study years.
本研究旨在描述溃疡性结肠炎（UC）和克罗恩病（CD）住院治疗的趋势、住院结局及疾病负担。我们的研究纳入了2008年、2010年、2012年、2014年、2016年和2018年全国住院患者样本中主要出院诊断为CD和UC的住院数据。排除了年龄≤18岁的个体及择期住院患者。2008年至2018年，我们注意到UC住院人数呈上升趋势（趋势<0.001）。然而，CD住院人数没有统计学上的显著趋势（趋势=0.249）。UC的总体住院死亡率从2008年的1.09%下降至2014年的0.42%（趋势<0.001）。此外，CD的住院死亡率也呈下降趋势，从2008年的0.28%降至2016年的0.17%（趋势=0.002）。2008年至2018年，UC的住院死亡几率显著高于CD。总之，在研究期间，CD和UC的死亡率均显著下降，但在所有研究年份中，UC住院患者的住院死亡几率更高。
