Fagni Filippo, Knitza Johannes, Krusche Martin, Kleyer Arnd, Tascilar Koray, Simon David
Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander University (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
Deutsches Zentrum fuer Immuntherapie, FAU Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany.
Front Med (Lausanne). 2021 Aug 11;8:718922. doi: 10.3389/fmed.2021.718922. eCollection 2021.
Psoriatic arthritis (PsA) is a chronic inflammatory disease that develops in up to 30% of patients with psoriasis. In the vast majority of cases, cutaneous symptoms precede musculoskeletal complaints. Progression from psoriasis to PsA is characterized by subclinical synovio-entheseal inflammation and often non-specific musculoskeletal symptoms that are frequently unreported or overlooked. With the development of increasingly effective therapies and a broad drug armamentarium, prevention of arthritis development through careful clinical monitoring has become priority. Identifying high-risk psoriasis patients before PsA onset would ensure early diagnosis, increased treatment efficacy, and ultimately better outcomes; ideally, PsA development could even be averted. However, the current model of care for PsA offers only limited possibilities of early intervention. This is attributable to the large pool of patients to be monitored and the limited resources of the health care system in comparison. The use of digital technologies for health (eHealth) could help close this gap in care by enabling faster, more targeted and more streamlined access to rheumatological care for patients with psoriasis. eHealth solutions particularly include telemedicine, mobile technologies, and symptom checkers. Telemedicine enables rheumatological visits and consultations at a distance while mobile technologies can improve monitoring by allowing patients to self-report symptoms and disease-related parameters continuously. Symptom checkers have the potential to direct patients to medical attention at an earlier point of their disease and therefore minimizing diagnostic delay. Overall, these interventions could lead to earlier diagnoses of arthritis, improved monitoring, and better disease control while simultaneously increasing the capacity of referral centers.
银屑病关节炎(PsA)是一种慢性炎症性疾病,多达30%的银屑病患者会患上该病。在绝大多数情况下,皮肤症状先于肌肉骨骼症状出现。从银屑病发展到PsA的过程以亚临床滑膜附着点炎症为特征,且常伴有非特异性肌肉骨骼症状,这些症状往往未被报告或忽视。随着越来越有效的治疗方法和广泛的药物储备的发展,通过仔细的临床监测预防关节炎的发展已成为首要任务。在PsA发病前识别高危银屑病患者将确保早期诊断、提高治疗效果,并最终获得更好的结果;理想情况下,甚至可以避免PsA的发生。然而,目前PsA的护理模式提供的早期干预可能性有限。这归因于需要监测的患者数量众多,而相比之下医疗保健系统的资源有限。利用数字健康技术(eHealth)可以通过使银屑病患者更快、更有针对性且更高效地获得风湿病护理来帮助弥补护理差距。eHealth解决方案尤其包括远程医疗、移动技术和症状检查器。远程医疗能够实现远程风湿病就诊和咨询,而移动技术可以通过允许患者持续自我报告症状和疾病相关参数来改善监测。症状检查器有可能在疾病的早期阶段引导患者就医,从而最大限度地减少诊断延迟。总体而言,这些干预措施可以导致关节炎的早期诊断、改善监测和更好的疾病控制,同时提高转诊中心的能力。