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1
Current Knowledge and Challenges on the Development of a Dietary Glucosinolate Database in the United States.美国膳食硫代葡萄糖苷数据库开发的当前知识与挑战
Curr Dev Nutr. 2021 Jul 23;5(8):nzab102. doi: 10.1093/cdn/nzab102. eCollection 2021 Aug.
2
Glucosinolates in Vegetables: Characterization and Factors That Influence Distribution, Content, and Intake.蔬菜中的硫代葡萄糖苷：特征描述以及影响其分布、含量和摄取的因素。
Annu Rev Food Sci Technol. 2021 Mar 25;12:485-511. doi: 10.1146/annurev-food-070620-025744. Epub 2021 Jan 19.
3
Development of a food composition database for the estimation of dietary intakes of glucosinolates, the biologically active constituents of cruciferous vegetables.开发一个用于估算十字花科蔬菜生物活性成分硫代葡萄糖苷膳食摄入量的食物成分数据库。
Br J Nutr. 2003 Sep;90(3):687-97. doi: 10.1079/bjn2003917.
4
Genetic analysis of glucosinolate variability in broccoli florets using genome-anchored single nucleotide polymorphisms.利用基因组锚定单核苷酸多态性对西兰花小花中硫代葡萄糖苷变异性进行遗传分析。
Theor Appl Genet. 2015 Jul;128(7):1431-47. doi: 10.1007/s00122-015-2517-x. Epub 2015 May 1.
5
Glucosinolate and isothiocyanate intakes are inversely associated with breast cancer risk: a case-control study in China.类葡萄糖硫苷和异硫氰酸酯的摄入量与乳腺癌风险呈负相关：中国的一项病例对照研究。
Br J Nutr. 2018 Apr;119(8):957-964. doi: 10.1017/S0007114518000600.
6
Glucosinolates from pak choi and broccoli induce enzymes and inhibit inflammation and colon cancer differently.小白菜和西兰花中的硫代葡萄糖苷对酶的诱导作用以及对炎症和结肠癌的抑制作用存在差异。
Food Funct. 2014 Jun;5(6):1073-81. doi: 10.1039/c3fo60676g. Epub 2014 Apr 9.
7
Glucosinolate Content in Brassica Genetic Resources and Their Distribution Pattern within and between Inner, Middle, and Outer Leaves.十字花科遗传资源中的硫代葡萄糖苷含量及其在内叶、中叶和外叶内部和之间的分布模式。
Plants (Basel). 2020 Oct 23;9(11):1421. doi: 10.3390/plants9111421.
8
Expression profiles of glucosinolate biosynthetic genes in turnip (Brassica rapa var. rapa) at different developmental stages and effect of transformed flavin-containing monooxygenase genes on hairy root glucosinolate content.不同发育阶段萝卜（ Brassica rapa var. rapa ）中硫代葡萄糖苷生物合成基因的表达谱及黄素单加氧酶基因转化对毛状根硫代葡萄糖苷含量的影响。
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9
Profiling of Individual Desulfo-Glucosinolate Content in Cabbage Head ( var. ) Germplasm.白菜品种（var.）个体硫代葡萄糖苷含量分析。
Molecules. 2020 Apr 17;25(8):1860. doi: 10.3390/molecules25081860.
10
MYB transcription factors regulate glucosinolate biosynthesis in different organs of Chinese cabbage (Brassica rapa ssp. pekinensis).MYB 转录因子调控大白菜（ Brassica rapa ssp. pekinensis ）不同器官中的硫代葡萄糖苷生物合成。
Molecules. 2013 Jul 22;18(7):8682-95. doi: 10.3390/molecules18078682.

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Determination of progoitrin, sinigrin, and glucoerucin contents and the expression pattern of aliphatic glucosinolates biosynthesis pathway genes in different maturity groups of cauliflower.花椰菜不同成熟组中前甲状腺肿素、黑芥子硫苷酸钾和葡萄糖芥苷含量的测定以及脂肪族硫代葡萄糖苷生物合成途径基因的表达模式
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'Superfoods': Reliability of the Information for Consumers Available on the Web.“超级食物”：网络上可供消费者获取的信息的可靠性
Foods. 2023 Jan 26;12(3):546. doi: 10.3390/foods12030546.
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Beneficial Health Effects of Glucosinolates-Derived Isothiocyanates on Cardiovascular and Neurodegenerative Diseases.芥子油苷衍生的异硫氰酸盐对心血管和神经退行性疾病的有益健康影响。
Molecules. 2022 Jan 19;27(3):624. doi: 10.3390/molecules27030624.

本文引用的文献

1
Glucosinolates in Vegetables: Characterization and Factors That Influence Distribution, Content, and Intake.蔬菜中的硫代葡萄糖苷：特征描述以及影响其分布、含量和摄取的因素。
Annu Rev Food Sci Technol. 2021 Mar 25;12:485-511. doi: 10.1146/annurev-food-070620-025744. Epub 2021 Jan 19.
2
Effects of cooking methods on total isothiocyanate yield from cruciferous vegetables.烹饪方法对十字花科蔬菜中总异硫氰酸盐产量的影响。
Food Sci Nutr. 2020 Sep 9;8(10):5673-5682. doi: 10.1002/fsn3.1836. eCollection 2020 Oct.
3
Protective Effect of Isothiocyanates from Cruciferous Vegetables on Breast Cancer: Epidemiological and Preclinical Perspectives.十字花科蔬菜异硫氰酸盐对乳腺癌的保护作用：流行病学和临床前观点。
Anticancer Agents Med Chem. 2021;21(11):1413-1430. doi: 10.2174/1871520620666200924104550.
4
Glucosinolate structural diversity, identification, chemical synthesis and metabolism in plants.植物中硫代葡萄糖苷的结构多样性、鉴定、化学合成与代谢。
Phytochemistry. 2020 Jan;169:112100. doi: 10.1016/j.phytochem.2019.112100. Epub 2019 Nov 23.
5
Profiling glucosinolate metabolites in human urine and plasma after broccoli consumption using non-targeted and targeted metabolomic analyses.食用西兰花后采用非靶向和靶向代谢组学分析对人尿液和血浆中的硫代葡萄糖苷代谢物进行分析。
Food Chem. 2020 Mar 30;309:125660. doi: 10.1016/j.foodchem.2019.125660. Epub 2019 Oct 14.
6
The Glucosinolates: A Sulphur Glucoside Family of Mustard Anti-Tumour and Antimicrobial Phytochemicals of Potential Therapeutic Application.硫代葡萄糖苷：一种具有潜在治疗应用价值的芥菜类抗肿瘤和抗菌植物化学物质的硫苷家族
Biomedicines. 2019 Aug 19;7(3):62. doi: 10.3390/biomedicines7030062.
7
Food Composition at Present: New Challenges.目前的食物成分：新的挑战。
Nutrients. 2019 Jul 25;11(8):1714. doi: 10.3390/nu11081714.
8
Impact of Glucosinolate Content in Broccoli (Brassica oleracea (Italica Group)) on Growth of Pseudomonas marginalis, a Causal Agent of Bacterial Soft Rot.西兰花（甘蓝（意大利组））中硫代葡萄糖苷含量对细菌性软腐病病原菌边缘假单胞菌生长的影响
Plant Dis. 2002 Jun;86(6):629-632. doi: 10.1094/PDIS.2002.86.6.629.
9
Anti-Carcinogenic Glucosinolates in Cruciferous Vegetables and Their Antagonistic Effects on Prevention of Cancers.十字花科蔬菜中的抗癌性硫代葡萄糖苷及其对癌症预防的拮抗作用。
Molecules. 2018 Nov 15;23(11):2983. doi: 10.3390/molecules23112983.
10
The Challenge of Reforming Nutritional Epidemiologic Research.营养流行病学研究改革的挑战
JAMA. 2018 Sep 11;320(10):969-970. doi: 10.1001/jama.2018.11025.

美国膳食硫代葡萄糖苷数据库开发的当前知识与挑战

Current Knowledge and Challenges on the Development of a Dietary Glucosinolate Database in the United States.

作者信息

Wu Xianli, Pehrsson Pamela R

机构信息

Methods and Application of Food Composition Laboratory, USDA ARS Beltsville Human Nutrition Research Center, Beltsville, MD, USA.

出版信息

Curr Dev Nutr. 2021 Jul 23;5(8):nzab102. doi: 10.1093/cdn/nzab102. eCollection 2021 Aug.

DOI:10.1093/cdn/nzab102
PMID:34458665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8386921/
Abstract

Glucosinolates (GSLs) are a group of cancer chemopreventive sulfur-containing compounds found primarily in vegetables. The goals of this study were to summarize the current knowledge and discuss the challenges of developing a dietary GSL database for US foods. A systematic literature search was conducted for the period 1980-2020. Thirty articles were found to meet all inclusion and exclusion criteria; 27 GSLs were reported in 16 different vegetables. GSLs identified and quantified ranged from 3 for winter cress to 16 for cabbage. In general, the experimental designs of these 30 studies did not fully consider the factors related to the data quality. Enormous variations of GSLs are observed between different vegetables and in the same vegetables. In conclusion, the studies on GSLs in commonly consumed vegetables are still limited, and some data may be outdated. Currently available data are not sufficient to develop a valid GSL database in the United States.

摘要

硫代葡萄糖苷（GSLs）是一类主要存在于蔬菜中的具有癌症化学预防作用的含硫化合物。本研究的目的是总结当前的知识，并讨论为美国食品建立膳食GSL数据库所面临的挑战。我们对1980年至2020年期间的文献进行了系统检索。发现有30篇文章符合所有纳入和排除标准；在16种不同蔬菜中报告了27种硫代葡萄糖苷。所鉴定和定量的硫代葡萄糖苷数量从水田芥的3种到卷心菜的16种不等。总体而言，这30项研究的实验设计并未充分考虑与数据质量相关的因素。在不同蔬菜之间以及同一蔬菜内部，硫代葡萄糖苷的含量都存在巨大差异。总之，关于常见食用蔬菜中硫代葡萄糖苷的研究仍然有限，且一些数据可能已过时。目前可获得的数据不足以在美国建立一个有效的硫代葡萄糖苷数据库。