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哥伦比亚波哥大与新型冠状病毒感染相关的因素:一项大型流行病学监测研究的结果

Factors Associated With SARS-CoV-2 Infection in Bogotá, Colombia: Results From a Large Epidemiological Surveillance Study.

作者信息

Varela Andrea Ramirez, Florez Luis Jorge Hernandez, Tamayo-Cabeza Guillermo, Contreras-Arrieta Sandra, Restrepo Silvia Restrepo, Laajaj Rachid, Gutierrez Giancarlo Buitrago, Guevara Yenny Paola Rueda, Caballero-Díaz Yuldor, Florez Martha Vives, Osorio Elkin, Barbieri Ignacio Sarmiento, Sanchez Daniela Rodriguez, Nuñez Leonardo Leon, Bernal Raquel, Oliveros Sofía Rios, Zapata Leonardo Salas, Guevara-Suarez Marcela, Uribe Alejandro Gaviria, Behrentz Eduardo

机构信息

School of Medicine, Universidad de los Andes, Bogotá, Colombia.

Department of Food and Chemical Engineering, Universidad de los Andes, Bogotá, Colombia.

出版信息

Lancet Reg Health Am. 2021 Oct;2:100048. doi: 10.1016/j.lana.2021.100048. Epub 2021 Aug 23.

Abstract

BACKGROUND

Epidemiologic surveillance of COVID-19 is essential to collect and analyse data to improve public health decision making during the pandemic. There are few initiatives led by public-private alliances in Colombia and Latin America. The CoVIDA project contributed with RT-PCR tests for SARS-CoV-2 in mild or asymptomatic populations in Bogotá. The present study aimed to determine the factors associated with SARS-CoV-2 infection in working adults.

METHODS

COVID-19 intensified sentinel epidemiological surveillance study, from April 18, 2020, to March 29, 2021. The study included people aged 18 years or older without a history of COVID-19. Two main occupational groups were included: healthcare and essential services workers with high mobility in the city. Social, demographic, and health-related factors were collected via phone survey. Afterwards, the molecular test was conducted to detect SARS-CoV-2 infection.

FINDINGS

From the 58,638 participants included in the study, 3,310 (5·6%) had a positive result. A positive result was associated with the age group (18-29 years) compared with participants aged 60 or older, participants living with more than three cohabitants, living with a confirmed case, having no affiliation to the health system compared to those with social health security, reporting a very low socioeconomic status compared to those with higher socioeconomic status, and having essential occupations compared to healthcare workers.

INTERPRETATION

The CoVIDA study showed the importance of intensified epidemiological surveillance to identify groups with increased risk of infection. These groups should be prioritised in the screening, contact tracing, and vaccination strategies to mitigate the pandemic.

FUNDING

The CoVIDA study was funded through donors managed by the philanthropy department of Universidad de los Andes.

摘要

背景

2019冠状病毒病(COVID-19)的流行病学监测对于收集和分析数据以改善疫情期间的公共卫生决策至关重要。在哥伦比亚和拉丁美洲,由公私联盟牵头的此类举措很少。CoVIDA项目为波哥大轻症或无症状人群的严重急性呼吸综合征冠状病毒2(SARS-CoV-2)提供逆转录聚合酶链反应(RT-PCR)检测。本研究旨在确定在职成年人中与SARS-CoV-2感染相关的因素。

方法

2020年4月18日至2021年3月29日进行的COVID-19强化哨点流行病学监测研究。该研究纳入了18岁及以上且无COVID-19病史的人群。包括两个主要职业群体:城市中流动性高的医护人员和基本服务工作者。通过电话调查收集社会、人口和健康相关因素。之后,进行分子检测以检测SARS-CoV-2感染。

结果

在纳入研究的58638名参与者中,3310名(5.6%)检测结果呈阳性。与60岁及以上的参与者相比,18 - 29岁年龄组检测结果呈阳性;与三名以上同居者共同生活的参与者、与确诊病例共同生活的参与者、与有社会健康保障的参与者相比没有卫生系统隶属关系的参与者、与社会经济地位较高的参与者相比社会经济地位极低的参与者,以及与医护人员相比从事基本职业的参与者。

解读

CoVIDA研究表明强化流行病学监测对于识别感染风险增加的群体的重要性。在筛查、接触者追踪和疫苗接种策略中应优先考虑这些群体,以减轻疫情影响。

资金来源

CoVIDA研究由安第斯大学慈善部门管理的捐赠者资助。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5580/9904112/4f76eb8be68f/gr1.jpg

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