Department of Nursing, Affiliated Hospital of Nantong University, Nantong University, 20th Xisi Road, Nantong, 226001, China.
Department of Neurosurgery, Affiliated Hospital of Nantong University, Nantong University, 20th Xisi Road, Nantong, 226001, China.
Support Care Cancer. 2022 Feb;30(2):1231-1241. doi: 10.1007/s00520-021-06504-2. Epub 2021 Aug 30.
Sleep disturbance is common in meningioma patients and may lead to disease aggravation and decreases health-related quality of life (HRQoL). However, the sleep quality of meningioma patients newly diagnosed and ready for surgery has not been well clarified in China. This study aims to evaluate the prevalence, correlates, and impact of sleep disturbance among Chinese meningioma patients.
In this cross-sectional study, meningioma patients were recruited from the Affiliated Hospital of Nantong University from January 2020 to November 2020. A series of questionnaires were applied: the 0-10 Numerical Rating Scale (NRS), the Hospital Anxiety and Depression Scale (HADS), the Multidimensional Fatigue Inventory (MFI-20), the Epworth Sleepiness Scale (ESS), the Short-Form 36 (SF-36), the Pittsburgh Sleep Quality Index (PSQI). Independent samples t test, Mann-Whitney U test, chi-square analysis, Pearson/Spearman correlation, and binary logistic regression were used to analyze the data.
One hundred meningioma patients completed the questionnaires. Sleep disturbance affected 43% of the meningioma patients and was linked to many concomitant symptoms, such as headache, fatigue, anxiety, and depression. Binary logistic regression indicated that fatigue and headache were independently associated with sleep disturbance of meningioma patients. Meanwhile, severe sleep disturbance led to lower quality of life.
These findings demonstrated that a considerable number of meningioma patients newly diagnosed and ready for surgery suffered from sleep disturbance, potentially contributing to impair HRQoL. Medical personnel should pay more attention to meningioma patients with sleep disturbance and take effective measures to improve sleep quality, with the ultimate goal to improve their HRQoL.
睡眠障碍在脑膜瘤患者中很常见，可能导致疾病恶化和降低健康相关生活质量（HRQoL）。然而，中国尚未明确新诊断和准备手术的脑膜瘤患者的睡眠质量。本研究旨在评估中国脑膜瘤患者睡眠障碍的流行率、相关性和影响。
在这项横断面研究中，从 2020 年 1 月至 2020 年 11 月，南通大学附属医院招募了脑膜瘤患者。应用了一系列问卷：0-10 数字评定量表（NRS）、医院焦虑和抑郁量表（HADS）、多维疲劳量表（MFI-20）、Epworth 嗜睡量表（ESS）、简明健康状况量表 36 项（SF-36）、匹兹堡睡眠质量指数（PSQI）。采用独立样本 t 检验、Mann-Whitney U 检验、卡方分析、Pearson/Spearman 相关分析和二元逻辑回归分析数据。
100 名脑膜瘤患者完成了问卷。43%的脑膜瘤患者存在睡眠障碍，且与头痛、疲劳、焦虑和抑郁等多种伴随症状相关。二元逻辑回归表明，疲劳和头痛与脑膜瘤患者的睡眠障碍独立相关。同时，严重的睡眠障碍导致生活质量下降。
这些发现表明，相当数量的新诊断和准备手术的脑膜瘤患者存在睡眠障碍，可能会损害 HRQoL。医务人员应更加关注有睡眠障碍的脑膜瘤患者，并采取有效措施改善睡眠质量，最终目标是提高其 HRQoL。
