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Five-day water-only fasting decreased metabolic-syndrome risk factors and increased anti-aging biomarkers without toxicity in a clinical trial of normal-weight individuals.

作者信息

Jiang Yanyu, Yang Xi, Dong Changsheng, Lu Yun, Yin Hongmei, Xiao Biying, Yang Xuguang, Chen Wenlian, Cheng Wei, Tian Hechuan, Guo Lin, Hu Xiaobo, Fang Hong, Chen Weiqin, Li Zhen, Zhou Wenqin, Sun Weijun, Guo Xiyan, Li Shaobin, Lin Yuli, He Rui, Chen Xiaoyun, Liu Di, Zhang Minghui, Zhang Yanmei, Zhao Hu, Zheng Peiyong, Seyfried Thomas N, Hoffman Robert M, Jia Wei, Ji Guang, Jia Lijun

机构信息

Cancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Department of Clinical Laboratory, Longhua Hospital, Shanghai University of Traditional Chinese, Shanghai, China.

出版信息

Clin Transl Med. 2021 Aug;11(8):e502. doi: 10.1002/ctm2.502.

DOI:10.1002/ctm2.502
PMID:34459130
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8320652/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b115/8320652/ea049bcd4295/CTM2-11-e502-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b115/8320652/2353392ecbba/CTM2-11-e502-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b115/8320652/ea049bcd4295/CTM2-11-e502-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b115/8320652/2353392ecbba/CTM2-11-e502-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b115/8320652/ea049bcd4295/CTM2-11-e502-g002.jpg

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Cell Metab. 2019 Sep 3;30(3):462-476.e6. doi: 10.1016/j.cmet.2019.07.016. Epub 2019 Aug 27.
2
2 years of calorie restriction and cardiometabolic risk (CALERIE): exploratory outcomes of a multicentre, phase 2, randomised controlled trial.热量限制与心脏代谢风险持续 2 年(CALERIE):一项多中心、2 期、随机对照试验的探索性结果。
Lancet Diabetes Endocrinol. 2019 Sep;7(9):673-683. doi: 10.1016/S2213-8587(19)30151-2. Epub 2019 Jul 11.
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Fasting and cancer: molecular mechanisms and clinical application.
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Front Microbiol. 2023 Oct 3;14:1265425. doi: 10.3389/fmicb.2023.1265425. eCollection 2023.
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Efficacy and safety of prolonged water fasting: a narrative review of human trials.长期禁食水的疗效和安全性:人体试验的叙述性综述。
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A Six-Week Follow-Up Study on the Sustained Effects of Prolonged Water-Only Fasting and Refeeding on Markers of Cardiometabolic Risk.一项为期六周的随访研究,旨在探讨长时间只饮水禁食和再喂养对心血管代谢风险标志物的持续影响。
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