在牙槽骨成形术中使用与不使用脱水人羊膜/绒毛膜进行伤口愈合疗效的比较评估：一项初步研究。

Comparative evaluation of the efficacy of wound healing with and without dehydrated human amniotic/chorionic membrane in alveoloplasty: a pilot study.

作者信息

Gajul Monica, Bhate Kalyani, Awate Sayali, Kakodkar Pradnya, Shah Sonal

机构信息

Department of Oral & Maxillofacial Surgery, Dr. D. Y. Patil Vidyapeeth, Pune, India.

出版信息

J Korean Assoc Oral Maxillofac Surg. 2021 Aug 31;47(4):279-285. doi: 10.5125/jkaoms.2021.47.4.279.

OBJECTIVES

Wound healing is an integral part of any surgical procedure. Appropriate wound closure is critical to any successful surgical procedure, especially intraoral procedures. Various factors aid in wound healing, both pharmacological and non-pharmacological. Dehydrated human amniotic/chorionic membrane (dHACM) is an emerging bioinert material that contains anti-inflammatory properties, angiogenetic properties, osteogenic potential, and various growth factors. The purpose of this study was to evaluate the efficacy of wound healing properties of dHACM in bilateral alveoloplasty patients.

MATERIALS AND METHODS

A prospective split-mouth study was conducted on 10 patients. Site A received sutures with dHACM and site B was sutured without dHACM. Wound healing was assessed with the Landry, Turnbull, and Howley Index.

RESULTS

Sites A and site B were compared. A <0.05 and a test value of 22 was obtained, indicating a statistical difference between the two sites.

CONCLUSION

Our study showed better healing with dHACM than without.

目的

伤口愈合是任何外科手术不可或缺的一部分。合适的伤口闭合对于任何成功的外科手术至关重要，尤其是口腔内手术。多种因素有助于伤口愈合，包括药理学和非药理学因素。脱水人羊膜/绒毛膜（dHACM）是一种新兴的生物惰性材料，具有抗炎特性、血管生成特性、成骨潜能和多种生长因子。本研究的目的是评估dHACM对双侧牙槽成形术患者伤口愈合特性的疗效。