Khalilzadeh Somayyeh, Eftekhar Tahereh, Rahimi Roja, Mehriardestani Mozhgan, Tabarrai Malihe
Department of Persian medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Department of Obstetrics and Gynecology, Tehran University of Medical Sciences, Tehran, Iran.
Galen Med J. 2019 May 8;8:e1270. doi: 10.31661/gmj.v8i0.1270. eCollection 2019.
Vaginitis is one of the most common gynecological problems in reproductive age. Because of the limitations of the conventional drugs, identification of new pharmacological interventions for this disease seems to be necessary. The purpose of this article is to review the medicinal herbs mentioned for the treatment of vaginitis by the great Iranian scientist, Avicenna, in his book " " to scientifically demonstrate their effects and their potential to be used as complementary therapies. The medicinal plants listed for vaginitis treatment in " " were extracted. The scientific name and English common name of the given medicinal plants were searched in databases including PubMed, Scopus, and Cochrane Library until December 2017 to obtain any in vitro, animal, and clinical evidence related to vaginitis. Various pharmacological activities, including anti-inflammatory, wound healing, antimicrobial, antifungal, analgesic, and anti-prostaglandin E2, have been demonstrated for medicinal plants emphasized by for vaginitis. Randomized controlled trials (RCTs) on Myrtus reported an improvement in the treatment of bacterial vaginosis. Four RCTs on pomegranate indicated a reduction in inflammatory factors in the patients. Medicinal herbs offered in Herbal Medicine are valuable sources for the treatment of various diseases. Effects and pharmacodynamics having been proved by conventional medicine confirm the effectiveness of these herbs. Therefore, these plants can be used in the treatment of vaginitis thanks to further clinical studies.
阴道炎是育龄期最常见的妇科问题之一。由于传统药物的局限性，似乎有必要寻找针对该疾病的新的药物干预措施。本文的目的是回顾伟大的伊朗科学家阿维森纳在其著作《》中提到的用于治疗阴道炎的草药，以科学地证明它们的作用以及作为辅助疗法使用的潜力。提取了《》中列出的用于治疗阴道炎的药用植物。在包括PubMed、Scopus和Cochrane图书馆在内的数据库中搜索给定药用植物的科学名称和英文通用名称，直至2017年12月，以获取与阴道炎相关的任何体外、动物和临床证据。对于阿维森纳强调的用于阴道炎的药用植物，已证明其具有多种药理活性，包括抗炎、伤口愈合、抗菌、抗真菌、止痛和抗前列腺素E2。关于香桃木的随机对照试验报告称，其对细菌性阴道炎的治疗有改善作用。关于石榴的四项随机对照试验表明，患者体内的炎症因子有所减少。《草药医学》中提到的药用植物是治疗各种疾病的宝贵来源。传统医学已证明的作用和药效学证实了这些草药的有效性。因此，经过进一步的临床研究，这些植物可用于治疗阴道炎。
