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病态窦房结综合征患者植入双腔起搏器后,行低位房间隔起搏致 P 波时限缩短:病例报告。

Patient with sick sinus syndrome and implanted dual-chamber pacemaker with reduced P-wave duration following low interatrial septal pacing: Case report.

机构信息

Department of Emergency Medicine, Wroclaw Medical University, Wroclaw, Poland.

Klodzko County Hospital, Klodzko, Poland.

出版信息

Medicine (Baltimore). 2021 Sep 3;100(35):e27076. doi: 10.1097/MD.0000000000027076.

DOI:10.1097/MD.0000000000027076
PMID:34477142
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8415954/
Abstract

INTRODUCTION

A dual-chamber pacemaker (DDD/R) for a sinus node disease is sometimes referred to as a physiological pacemaker as it maintains atrioventricular synchrony, however several clinical trials have proved its inferiority to a nonphysiological single-chamber ventricular back-up pacing.

PATIENT CONCERNS

A subject of the study is a 74-year-old woman with a sick sinus syndrome (SSS) and a previously implanted physiological DDD/R pacemaker. The SSS was diagnosed because of patient's very slow sinus rhythm of about 36 bpm, and due to several episodes of dizziness. After the DDD/R implantation the percentage of atrial pacing approached 100%, with almost none ventricular pacing.

DIAGNOSES

Sick sinus syndrome, complete Bachmann's bundle block, atrial fibrillation, atrial flutter.

INTERVENTIONS

The patient was previously implanted with a physiological DDD/R pacemaker. Several years after the implantation, the atrial fibrillation was diagnosed and the pulmonary vein isolation was then performed by cryoablation. During the follow-up after pulmonary vein isolation, the improvement of mitral filling parameters was assessed using echocardiography. Shortly thereafter the patient developed the persistent paroxysm of a typical atrial flutter which was successfully terminated using a radiofrequency ablation. No recurrence thereof has been observed ever since (24 months).

OUTCOMES

The atrial electrode of the pacing system was implanted within the low interatrial septal region that resulted in a reduced P-wave duration compared to native sinus rhythm P-waves. The said morphology was deformed because of the complete Bachmann bundle block. That approach, despite a nonphysiological direction of an atrial activation, yielded relatively short P-waves (paced P-wave: 179 ms vs intrinsic sinus P-wave: 237 ms). It also contributed to a significantly shorter PR interval (paced PR: 204 ms vs sinus rhythm PR: 254 ms).

CONCLUSIONS

The authors took into consideration different aspects of alternative right atrial pacing sites. This report has shown that in some patients with a sinus node disease, low interatrial septal pacing can reduce the P-wave duration but does not prevent from the development of atrial arrhythmias.

摘要

引言

双腔起搏器(DDD/R)用于治疗窦房结疾病,有时被称为生理性起搏器,因为它可以维持房室同步,但多项临床试验已经证明其不如非生理性单腔心室备用起搏。

患者关注

研究对象为一名 74 岁女性,患有病态窦房结综合征(SSS)和之前植入的生理性 DDD/R 起搏器。SSS 的诊断是因为患者的窦性节律非常缓慢,约为 36 次/分,并且出现了几次头晕。DDD/R 植入后,心房起搏的比例接近 100%,几乎没有心室起搏。

诊断

病态窦房结综合征,完全巴赫曼束阻滞,心房颤动,心房扑动。

干预措施

患者之前植入了生理性 DDD/R 起搏器。植入后几年,诊断出心房颤动,然后通过冷冻消融进行肺静脉隔离。肺静脉隔离后随访期间,使用超声心动图评估二尖瓣充盈参数的改善情况。此后不久,患者发生典型的持续性心房扑动阵发性发作,成功使用射频消融终止。此后从未再次发作(24 个月)。

结果

起搏系统的心房电极植入于心房低位中隔区,与窦性节律 P 波相比,P 波时限缩短。由于完全巴赫曼束阻滞,该形态发生了变形。尽管心房激活的方向是非生理性的,但这种方法仍产生了相对较短的 P 波(起搏 P 波:179 毫秒比固有窦性 P 波:237 毫秒)。它还导致 PR 间隔显著缩短(起搏 PR:204 毫秒比窦性节律 PR:254 毫秒)。

结论

作者考虑了不同的替代右房起搏部位。本报告表明,在一些患有窦房结疾病的患者中,低位房间隔起搏可以缩短 P 波时限,但不能预防房性心律失常的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6a6/8415954/72ec391195d0/medi-100-e27076-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6a6/8415954/eb8209a419f6/medi-100-e27076-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6a6/8415954/72ec391195d0/medi-100-e27076-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6a6/8415954/eb8209a419f6/medi-100-e27076-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6a6/8415954/72ec391195d0/medi-100-e27076-g002.jpg

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