Department of Emergency Medicine, Wroclaw Medical University, Wroclaw, Poland.
Klodzko County Hospital, Klodzko, Poland.
Medicine (Baltimore). 2021 Sep 3;100(35):e27076. doi: 10.1097/MD.0000000000027076.
A dual-chamber pacemaker (DDD/R) for a sinus node disease is sometimes referred to as a physiological pacemaker as it maintains atrioventricular synchrony, however several clinical trials have proved its inferiority to a nonphysiological single-chamber ventricular back-up pacing.
A subject of the study is a 74-year-old woman with a sick sinus syndrome (SSS) and a previously implanted physiological DDD/R pacemaker. The SSS was diagnosed because of patient's very slow sinus rhythm of about 36 bpm, and due to several episodes of dizziness. After the DDD/R implantation the percentage of atrial pacing approached 100%, with almost none ventricular pacing.
Sick sinus syndrome, complete Bachmann's bundle block, atrial fibrillation, atrial flutter.
The patient was previously implanted with a physiological DDD/R pacemaker. Several years after the implantation, the atrial fibrillation was diagnosed and the pulmonary vein isolation was then performed by cryoablation. During the follow-up after pulmonary vein isolation, the improvement of mitral filling parameters was assessed using echocardiography. Shortly thereafter the patient developed the persistent paroxysm of a typical atrial flutter which was successfully terminated using a radiofrequency ablation. No recurrence thereof has been observed ever since (24 months).
The atrial electrode of the pacing system was implanted within the low interatrial septal region that resulted in a reduced P-wave duration compared to native sinus rhythm P-waves. The said morphology was deformed because of the complete Bachmann bundle block. That approach, despite a nonphysiological direction of an atrial activation, yielded relatively short P-waves (paced P-wave: 179 ms vs intrinsic sinus P-wave: 237 ms). It also contributed to a significantly shorter PR interval (paced PR: 204 ms vs sinus rhythm PR: 254 ms).
The authors took into consideration different aspects of alternative right atrial pacing sites. This report has shown that in some patients with a sinus node disease, low interatrial septal pacing can reduce the P-wave duration but does not prevent from the development of atrial arrhythmias.
双腔起搏器(DDD/R)用于治疗窦房结疾病,有时被称为生理性起搏器,因为它可以维持房室同步,但多项临床试验已经证明其不如非生理性单腔心室备用起搏。
研究对象为一名 74 岁女性,患有病态窦房结综合征(SSS)和之前植入的生理性 DDD/R 起搏器。SSS 的诊断是因为患者的窦性节律非常缓慢,约为 36 次/分,并且出现了几次头晕。DDD/R 植入后,心房起搏的比例接近 100%,几乎没有心室起搏。
病态窦房结综合征,完全巴赫曼束阻滞,心房颤动,心房扑动。
患者之前植入了生理性 DDD/R 起搏器。植入后几年,诊断出心房颤动,然后通过冷冻消融进行肺静脉隔离。肺静脉隔离后随访期间,使用超声心动图评估二尖瓣充盈参数的改善情况。此后不久,患者发生典型的持续性心房扑动阵发性发作,成功使用射频消融终止。此后从未再次发作(24 个月)。
起搏系统的心房电极植入于心房低位中隔区,与窦性节律 P 波相比,P 波时限缩短。由于完全巴赫曼束阻滞,该形态发生了变形。尽管心房激活的方向是非生理性的,但这种方法仍产生了相对较短的 P 波(起搏 P 波:179 毫秒比固有窦性 P 波:237 毫秒)。它还导致 PR 间隔显著缩短(起搏 PR:204 毫秒比窦性节律 PR:254 毫秒)。
作者考虑了不同的替代右房起搏部位。本报告表明,在一些患有窦房结疾病的患者中,低位房间隔起搏可以缩短 P 波时限,但不能预防房性心律失常的发生。