Traditional Chinese Medicine Department, Chengdu Eighth People's Hospital (Geriatric Hospital of Chengdu Medical College), Chengdu, China.
Clinical College, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Medicine (Baltimore). 2021 Sep 3;100(35):e27110. doi: 10.1097/MD.0000000000027110.
Constipation is one of the common complications of thoracolumbar compression fractures, which seriously affects the quality of life and increases pain of patients. External treatment of traditional Chinese medicine (TCM) has been widely used clinically for constipation after thoracolumbar compression fractures, but there are no systematic review and meta-analysis of its efficacy. Therefore, we will conduct this study to systematically evaluate the clinical effects of external treatment of TCM for patients with constipation after thoracolumbar compression fractures.
We will search the following electronic databases: PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infastructure, Chinese Biomedical Literatures Database, Chinese Scientific Journal Database, and Wanfang Database. Randomized controlled trials on the treatment of constipation after thoracolumbar compression fractures with external treatment of TCM published from inception to May 2021 will be included in the search scope. The observation group was treated with Simple external treatment of TCM (such as external application of Chinese medicine, Chinese drugs at the acupoint, acupuncture, moxibustion, etc) or external treatment of TCM combined with conventional treatment/nursing of Western medicine, while the control group only was treated by conventional treatment/nursing of Western medicine. After screening literatures, extracting data, and assessing the risk of bias in the included studies, meta-analysis will be performed by Revman 5.3 software.
This study is expected to provide an evidence of the efficacy of external treatment of TCM for constipation after thoracolumbar compression fractures.
The results of this meta-analysis may help provide evidence to determine whether external treatment of TCM can be effective interventions for thoracolumbar compression fractures patients with constipation.
INPLASY202150005.
便秘是胸腰椎压缩性骨折的常见并发症之一，严重影响患者的生活质量并增加其疼痛。中医外治法已广泛应用于胸腰椎压缩性骨折后便秘的临床治疗，但目前尚缺乏系统评价和荟萃分析。因此，我们将开展这项研究，系统评价中医外治法治疗胸腰椎压缩性骨折后便秘的临床疗效。
我们将检索以下电子数据库：PubMed、Embase、Cochrane 图书馆、Web of Science、中国知识基础设施（CNKI）、中国生物医学文献数据库、中国科学引文数据库和万方数据库。纳入从建库至 2021 年 5 月采用中医外治法治疗胸腰椎压缩性骨折后便秘的随机对照试验。观察组采用单纯中医外治法（如中药外敷、穴位敷贴、针刺、艾灸等）或中医外治法联合西医常规治疗/护理，对照组仅采用西医常规治疗/护理。筛选文献后，提取数据，并对纳入研究进行偏倚风险评估，采用 Revman 5.3 软件进行荟萃分析。
本研究有望为中医外治法治疗胸腰椎压缩性骨折后便秘提供疗效证据。
本荟萃分析的结果可能有助于确定中医外治法是否可作为胸腰椎压缩性骨折便秘患者的有效干预措施。
INPLASY202150005。
