复发性自发性气胸作为骨肉瘤转移的一种并发症：病例报告

Recurrent spontaneous pneumothoraxes as a complication of osteosarcoma metastases: a case report.

作者信息

Kleedehn Mark, Kovacs Sandor Krisztian, Fitzpatrick Brody

机构信息

Assistant Professor, Fellowship Director, Department of Interventional Radiology, University of Wisconsin- Madison School of Medicine and Public Health, Madison, Wisconsin.

GI/Liver Surgical Pathology Fellow, Department of Pathology and Lab Medicine, University of Wisconsin Hospitals and Clinics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin.

出版信息

Radiol Case Rep. 2021 Aug 25;16(11):3162-3167. doi: 10.1016/j.radcr.2021.07.061. eCollection 2021 Nov.

DOI:10.1016/j.radcr.2021.07.061

PMID:34484511

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8405954/

Abstract

Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. Osteosarcomas are highly aggressive tumors that historically have had a dismal prognosis. However, the survival rate has improved significantly with the addition of adjuvant and neoadjuvant chemotherapy. Here, we present a case report of a 13-year-old male with a history of a left humeral osteosarcoma whose course was complicated by recurrent sarcoma-related pneumothoraces. Despite recurrent pneumothoraces being a relatively uncommon complication of osteosarcoma, they present a great challenge to providing treatment that optimizes outcomes and quality of life for patients.

摘要

骨肉瘤是儿童和青少年中最常见的原发性恶性骨肿瘤。骨肉瘤是具有高度侵袭性的肿瘤，从历史上看，其预后一直很差。然而，辅助化疗和新辅助化疗的应用使生存率有了显著提高。在此，我们报告一例13岁男性病例，该患者有左肱骨骨肉瘤病史，其病程因复发性肉瘤相关气胸而复杂化。尽管复发性气胸是骨肉瘤相对罕见的并发症，但它们对提供优化患者治疗效果和生活质量的治疗构成了巨大挑战。