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疯狂吸电子烟与铺路石征,一例电子香烟/吸电子烟相关肺损伤(EVALI),胸部CT显示铺路石征。

Crazy vaping and crazy-paving, a case of E-Cigarette/Vaping-Associated Lung Injury (EVALI) with chest CT showing crazy-paving pattern.

作者信息

Roman Sherif, Millet Christopher, Geris Shady, Manickam Rajapriya, Mechineni Ashesha

机构信息

Department of Medicine, St. Joseph's University Medical Center, NJ, USA.

Department of Pulmonary/Critical Care, St. Joseph's University Medical Center, NJ, USA.

出版信息

Radiol Case Rep. 2021 Aug 26;16(11):3208-3212. doi: 10.1016/j.radcr.2021.07.058. eCollection 2021 Nov.

DOI:10.1016/j.radcr.2021.07.058
PMID:34484520
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8405923/
Abstract

E-cigarettes are devices that generate an aerosol by heating a fluid containing multiple chemicals, such as nicotine, additives, and flavorings. They were developed to aid in smoking cessation and were promoted as socially acceptable, healthier, cheaper than conventional cigarettes. Multiple lung disorders related to e-cigarette use are reported, and they range from mild cases of pneumonitis to life-threatening lung disorders that may require intubation and mechanical ventilation. Most of the complications are due to the generation of various unknown and potentially harmful chemicals within the aerosol generated in the e-cigarette. These disorders are known collectively as e-cigarette/Vaping-associated lung injury (EVALI). E-cigarettes are marketed as safer alternatives to traditional cigarettes, with the highest rates of use are noted in young smokers. Given the significant prevalence of e-cigarettes use and their pulmonary complications, EVALI should be considered a potential etiology in the broad differential diagnosis of patients with pulmonary disease and a history of vaping. Herein, we present a case of cryptogenic organizing pneumonia with a chest C.T. showing a crazy-paving pattern in a patient with a history of vaping.

摘要

电子烟是通过加热含有多种化学物质(如尼古丁、添加剂和调味剂)的液体来产生气溶胶的装置。它们被开发用于帮助戒烟,并被宣传为社会可接受的、比传统香烟更健康、更便宜的产品。据报道,与使用电子烟相关的多种肺部疾病,范围从轻度肺炎病例到可能需要插管和机械通气的危及生命的肺部疾病。大多数并发症是由于电子烟产生的气溶胶中生成了各种未知且可能有害的化学物质。这些疾病统称为电子烟/雾化相关肺损伤(EVALI)。电子烟作为传统香烟更安全的替代品进行销售,在年轻吸烟者中使用率最高。鉴于电子烟使用的显著普遍性及其肺部并发症,在患有肺部疾病且有雾化史的患者的广泛鉴别诊断中,EVALI应被视为一种潜在病因。在此,我们报告一例隐源性机化性肺炎病例,该患者胸部CT显示有铺路石样改变,且有雾化史。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fd0/8405923/2badb7781fd1/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fd0/8405923/ceaf6785f445/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fd0/8405923/89ed95ad658b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fd0/8405923/2badb7781fd1/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fd0/8405923/ceaf6785f445/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fd0/8405923/89ed95ad658b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fd0/8405923/2badb7781fd1/gr3.jpg

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What are the mechanisms underlying vaping-induced lung injury?电子烟导致肺损伤的潜在机制是什么?
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