Jarjou'i Amir, Bogot Naama, Kalak George, Chen-Shuali Chen, Rokach Ariel, Izbicki Gabriel, Arish Nissim
Pulmonary Institute, Department of Medicine Shaare Zedek Medical Center Jerusalem Israel.
Faculty of Medicine Hebrew University of Jerusalem Jerusalem Israel.
Respirol Case Rep. 2021 Aug 31;9(10):e0839. doi: 10.1002/rcr2.839. eCollection 2021 Oct.
Pulmonary calcifications are usually incidental asymptomatic findings discovered on x-rays or computed tomography scans that can be easily overlooked, and their significance undermined, especially in a seemingly asymptomatic person. Calcifications can be a marker of chronicity or disease severity, and thus have diagnostic value. Rarely, calcification can be the direct cause of morbidity. Calcifications can be either localized or diffuse. Many diseases, in particular infectious diseases, can cause localized calcifications. Diffuse calcifications are less common and usually secondary to a handful of conditions such as dystrophic pulmonary calcifications, metastatic pulmonary calcifications, disseminated pulmonary ossifications and pulmonary alveolar microlithiasis. We describe three cases of diffuse pulmonary calcifications, review the different causes of diffuse pulmonary calcifications and provide some indicators on how to differentiate between them. Differentiating between the different types of pulmonary calcifications has significant implications on the management and prognosis of the patients, and thus it is important to distinguish between them.
肺部钙化通常是在X线或计算机断层扫描中偶然发现的无症状表现，很容易被忽视，其重要性也常被低估，尤其是在看似无症状的个体中。钙化可能是慢性疾病或疾病严重程度的标志，因此具有诊断价值。钙化很少会成为发病的直接原因。钙化可以是局部性的，也可以是弥漫性的。许多疾病，特别是传染病，可导致局部钙化。弥漫性钙化较少见，通常继发于少数几种情况，如营养不良性肺钙化、转移性肺钙化、播散性肺骨化和肺泡微石症。我们描述了3例弥漫性肺钙化病例，回顾了弥漫性肺钙化的不同病因，并提供了一些鉴别诊断的指标。区分不同类型的肺钙化对患者的管理和预后具有重要意义，因此区分它们很重要。
