Ferreira Paula Marques, Rato Inês Rueff, Rigor Joana, Mota Margarida
Centro Hospitalar de Vila Nova de Gaia Espinho EPE, Internal Medicine, Portugal.
JRSM Open. 2021 Aug 30;12(8):20542704211035995. doi: 10.1177/20542704211035995. eCollection 2021 Aug.
Hansen's disease, also known as leprosy, is an infection caused by the bacteria Mycobacterium leprae. The authors present the case of a 52-year-old man, born in Tondela and living in Espinho, with no pathological antecedents. The clinical picture began in April 2017, when macular lesions appeared in the lower limbs and rapidly progressed to the trunk and upper limbs, associated with complaints of pruritus but without alterations in the analytical study. After several topical and systemic treatments with glucocorticoids, antifungals, antibacterials and unsuccessful antihistamines, he was referred to an external consultation of Dermatology. He performed a biopsy of one of the lesions that revealed the definitive diagnosis: "Lepromatous Leprosy". After the biopsy result, he started triple treatment with rifampicin, clofazimine and dapsone with improvement of the condition.
麻风病，又称韩森氏病，是由麻风分枝杆菌引起的一种感染。作者介绍了一名52岁男性的病例，该患者出生于通德拉，居住在埃斯皮尼奥，无病史。临床表现始于2017年4月，当时下肢出现黄斑病变，并迅速蔓延至躯干和上肢，伴有瘙痒症状，但分析检查无异常。在接受了多种局部和全身的糖皮质激素、抗真菌药、抗菌药治疗以及抗组胺药治疗均无效后，他被转诊至皮肤科外部会诊。对其中一个病变进行活检后得出了明确诊断：“瘤型麻风”。活检结果出来后，他开始接受利福平、氯法齐明和氨苯砜的三联治疗，病情有所改善。
