Rojas Manuel, Rodríguez Yhojan, Zapata Elizabeth, Hernández Juan Carlos, Anaya Juan-Manuel
Center for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia.
Clinica del Occidente, Bogota, Colombia.
J Transl Autoimmun. 2021;4:100116. doi: 10.1016/j.jtauto.2021.100116. Epub 2021 Aug 31.
Liver compromise in critically ill patients with coronavirus disease 2019 (COVID-19) is common but usually transient and self-limited. However, liver tests on some patients continue to show abnormal results. Herein, a 29-year-old patient with clinical and histological features of cholangiopathy is presented. Despite treatment with ursodeoxycholic acid and cholestyramine, bilirubin and transaminase levels remained elevated. This case report raises awareness of the difficulty of managing this condition in patients with COVID-19.
2019冠状病毒病(COVID-19)危重症患者出现肝脏损害很常见,但通常是短暂的且具有自限性。然而,一些患者的肝功能检查结果持续异常。本文报告了一名29岁具有胆管病临床和组织学特征的患者。尽管使用了熊去氧胆酸和考来烯胺进行治疗,但胆红素和转氨酶水平仍持续升高。本病例报告提高了对COVID-19患者中这种情况管理难度的认识。