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利舒坦瞬感 2 型实时动态血糖监测系统对使用胰岛素泵的 1 型糖尿病患者糖尿病自我管理行为及血糖参数的影响

Effectiveness of the freestyle libre 2 flash glucose monitoring system on diabetes-self-management practices and glycemic parameters among patients with type 1 diabetes using insulin pump.

机构信息

Department of Endocrinology and Diabetes, Diabetes Treatment Center, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.

出版信息

Diabetes Metab Syndr. 2021 Sep-Oct;15(5):102265. doi: 10.1016/j.dsx.2021.102265. Epub 2021 Sep 1.

DOI:10.1016/j.dsx.2021.102265
PMID:34488057
Abstract

AIMS

To determine the effectiveness of Freestyle Libre 2 (FSL2) on diabetes-self-management (DSM) practices and glycemic parameters among patients with type 1 diabetes (T1D) using insulin pump.

METHODS

This prospective study was performed among 47 patients with T1D (13-21yrs) who self-tested their glucose levels by the conventional finger-prick method using blood glucose meters (BGM). Data related to glycemic profile i.e., mean time in range (TIR), mean time above range (TAR) mean time below range (TBR), mean glucose level, hemoglobin A1c (HbA1c), total daily dose of insulin (TDDI), frequency of glucose monitoring and DSM responses were collected at baseline and 12 weeks.

RESULTS

The mean TIR was 59.8 ± 12.6%, TAR 32.7 ± 11.6%, TBR 7.5 ± 4.3%, mean glycemic variability, standard deviation 63.2 ± 12.5 mg/dL, and the coefficient of variation 41.3 ± 11.4% at 12 weeks. At baseline, the HbA1c level was 8.3%, and at 12 weeks, it dropped to 7.9% (p = 0.064). Baseline glucose monitoring frequency through BGM was 2.4/day; however, after the patients employed the FSL2, a higher degree of frequency of glucose monitoring was evident at 12 weeks as 8.2/day (p < 0.001). Significant improvements were observed in all the DSM subscales at 12 weeks.

CONCLUSION

Using FSL2 was found to raise the patients' DSM levels and improved metabolic control.

摘要

目的

评估使用胰岛素输注泵的 1 型糖尿病(T1D)患者中,通过 Freestyle Libre 2(FSL2)进行糖尿病自我管理(DSM)实践对血糖参数的影响。

方法

本前瞻性研究纳入了 47 名使用血糖仪(BGM)通过指尖采血自我监测血糖的 T1D(13-21 岁)患者。收集了与血糖谱相关的数据,即平均血糖达标时间(TIR)、血糖高于目标范围时间(TAR)、血糖低于目标范围时间(TBR)、平均血糖水平、糖化血红蛋白(HbA1c)、胰岛素日总剂量(TDDI)、血糖监测频率以及 DSM 反应。这些数据分别在基线和 12 周时进行收集。

结果

在 12 周时,TIR 为 59.8±12.6%,TAR 为 32.7±11.6%,TBR 为 7.5±4.3%,平均血糖变异性标准差为 63.2±12.5mg/dL,变异系数为 41.3±11.4%。基线时 HbA1c 水平为 8.3%,12 周时降至 7.9%(p=0.064)。BGM 监测的基线血糖频率为 2.4 次/天;然而,在患者使用 FSL2 后,12 周时的血糖监测频率明显增加至 8.2 次/天(p<0.001)。12 周时所有 DSM 亚量表均有显著改善。

结论

使用 FSL2 可提高患者的 DSM 水平并改善代谢控制。

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