Kröpfl D, Krause R, Hartung R, Pfeiffer R, Behrendt H
Department of Urology, University of Essen Medical School, West German Tumor Center, FRG.
Urol Int. 1987;42(6):416-23. doi: 10.1159/000282006.
The authors have measured the concentration of biologically active heparin in the drainage fluid after ilioinguinal, pelvic and retroperitoneal lymphadenectomy. After s.c. heparin administration in the thighs high levels of heparin were found in the drainage fluid of all patients (up to 0.89 IU/ml). After s.c. heparin application in the upper arms, no measurable concentrations of heparin were detected. Lymph loss in these patients was considerably lower. According to this experience, subcutaneous application of heparin into the upper arms is to be recommended in patients who undergo lymphatic surgery of the lower part of the body.
作者们测定了腹股沟、盆腔及腹膜后淋巴结清扫术后引流液中生物活性肝素的浓度。在大腿皮下注射肝素后，所有患者的引流液中均发现了高水平的肝素（高达0.89 IU/ml）。在上臂皮下注射肝素后，未检测到可测量浓度的肝素。这些患者的淋巴液流失明显更低。根据这一经验，对于接受下半身淋巴手术的患者，建议在上臂皮下注射肝素。
