National-Local Joint Engineering Research Center of Rehabilitation Medicine Technology, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
BMJ Open. 2021 Sep 6;11(9):e046609. doi: 10.1136/bmjopen-2020-046609.
This study aimed to assess the cost-effectiveness of combined scalp acupuncture therapy with speech and language therapy for patients with Broca's aphasia after stroke.
A within-trial cost-effectiveness analysis.
Community health centres.
A total of 203 participants with Broca's aphasia after stroke who had been randomly assigned to receive scalp acupuncture with speech and language therapy (intervention) or speech and language therapy alone (control).
Both groups underwent speech and language therapy (30 min per day, 5 days a week, for 4 weeks), while the intervention group simultaneously received scalp acupuncture.
All outcomes were collected at baseline, and after the 4-week intervention and 12-week follow-up. Cost-effectiveness measures included the Chinese Rehabilitation Research Center Standard Aphasia Examination (CRRCAE) and Boston Diagnostic Aphasia Examination (BDAE). Cost-utility was evaluated using quality-adjusted life-years (QALYs). Incremental cost-effectiveness ratios were expressed, and sensitivity analysis was conducted.
The total cost to deliver the intervention was €4001.72, whereas it was €4323.57 for the control group. The incremental cost-effectiveness ratios showed that the intervention was cost-effective (€495.1 per BDAE grade gained; €1.8 per CRRCAE score gained; €4597.1 per QALYs gained) relative to the control over the 12 weeks. The intervention had a 56.4% probability of being cost-effective at the ¥50 696 (€6905.87) Gross Domestic Product (GDP) per capita threshold. Sensitivity analyses confirmed the robustness of the results.
Compared with speech and language therapy alone, the addition of scalp acupuncture was cost-effective in Chinese communities. As the costs of acupuncture services in China are likely to differ from other countries, these results should be carefully interpreted and remain to be confirmed in other populations.
ChiCTR-TRC-13003703.
本研究旨在评估头皮针联合言语语言治疗对脑卒中后布罗卡失语症患者的成本效益。
试验内的成本效益分析。
社区卫生中心。
共 203 名脑卒中后布罗卡失语症患者被随机分配接受头皮针联合言语语言治疗（干预组）或单纯言语语言治疗（对照组）。
两组均接受言语语言治疗（每天 30 分钟，每周 5 天，持续 4 周），同时干预组接受头皮针治疗。
所有结局均在基线、4 周干预后和 12 周随访时采集。成本效益测量指标包括中国康复研究中心标准失语症检查表（CRRCAE）和波士顿诊断性失语症检查表（BDAE）。使用质量调整生命年（QALYs）进行成本效用评估。增量成本效益比以欧元表示，并进行敏感性分析。
干预组的总费用为 4001.72 欧元，而对照组为 4323.57 欧元。增量成本效益比显示，干预组在 12 周时相对于对照组具有成本效益（BDAE 每提高 1 级增加 495.1 欧元；CRRCAE 每提高 1 分增加 1.8 欧元；QALYs 每增加 1 个增加 4597.1 欧元）。干预组在人均国内生产总值（GDP）50696 元（6905.87 欧元）的阈值下具有 56.4%的成本效益可能性。敏感性分析证实了结果的稳健性。
与单纯言语语言治疗相比，头皮针联合治疗在中国社区具有成本效益。由于中国针灸服务的成本可能与其他国家不同，因此应谨慎解释这些结果，并在其他人群中进一步验证。
ChiCTR-TRC-13003703。
