Aragón Institute of Engineering Research (i3A), University of Zaragoza, Spain.
Aragón Institute of Engineering Research (i3A), University of Zaragoza, Spain.
J Mech Behav Biomed Mater. 2021 Dec;124:104793. doi: 10.1016/j.jmbbm.2021.104793. Epub 2021 Aug 30.
The process of intraocular lens (IOL) delivery within the capsular bag during cataract surgery is crucial, as the integrity of the IOL, the injector and the ocular structures should be preserved at all times. This study aims to obtain the main parameters that affect the injection force exerted in the ejection of an intraocular lens (IOL) through syringe-type injectors. For that purpose, ejection tests were carried out in vitro, measuring the resistance force throughout the entire delivery process. The effect of IOL material, haptic design, IOL thickest area and ophthalmic viscosurgical device (OVD) was studied by ejecting seven IOLs with four syringe-type injectors of different sizes, 3.0, 2.2 and 1.8 mm. In all injectors, plate hydrophilic IOLs present the lowest resistance forces; hydrated C-loop hydrophobic IOLs present higher forces and the C-loop hydrophobic IOL in dry conditions presents the highest resistance forces. All IOLs could be properly delivered with an injector size of 2.2 mm, making injector sizes of 3.0 mm outdated. The injector size of 1.8 mm damaged several IOLs. IOL material and cartridge nozzle size were the most influential parameters in IOL delivery. IOL thickest area was also relevant but in a lesser extent whereas IOL haptic design was not as relevant.
在白内障手术中，将人工晶状体（IOL）输送到囊袋内的过程至关重要，因为始终应保持 IOL、注射器和眼部结构的完整性。本研究旨在获得影响通过注射器型注射器射出人工晶状体（IOL）时施加的注射力的主要参数。为此，通过在体外进行射出测试，测量了整个输送过程中的阻力。通过使用四个不同尺寸的 3.0、2.2 和 1.8mm 的注射器型注射器，对七种 IOL 进行射出测试，研究了 IOL 材料、襻设计、IOL 最厚区域和眼科黏弹剂（OVD）的影响。在所有注射器中，亲水板状 IOL 表现出的阻力最小；水合 C 型环疏水性 IOL 表现出更高的力，而干燥状态的 C 型环疏水性 IOL 表现出最高的阻力。所有 IOL 都可以通过 2.2mm 的注射器尺寸进行适当输送，因此 3.0mm 的注射器尺寸已过时。1.8mm 的注射器尺寸损坏了几个 IOL。IOL 材料和药筒喷嘴尺寸是 IOL 输送中最具影响力的参数。IOL 最厚区域也很重要，但影响较小，而 IOL 襻设计则不那么重要。
