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遗传性心律失常患者在 COVID-19 大流行期间的特殊表现。

Peculiar Aspects of Patients with Inherited Arrhythmias during the COVID-19 Pandemic.

机构信息

Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP - Brasil.

出版信息

Arq Bras Cardiol. 2021 Aug;117(2):394-403. doi: 10.36660/abc.20200391.

DOI:10.36660/abc.20200391
PMID:34495239
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8395786/
Abstract

Since December 2019 we have observed the rapid advance of the severe acute respiratory syndrome caused by the new coronavirus (SARS-CoV-2). The impact of the clinical course of a respiratory infection is little known in patients with hereditary arrhythmias, due to the low prevalence of these diseases. Patients who present with infectious conditions may exacerbate hidden or well-controlled primary arrhythmias, due to several factors, such as fever, electrolyte disturbances, drug interactions, adrenergic stress and, eventually, the septic patient's own myocardial damage. The aim of this review is to highlight the main challenges we may encounter during the Covid 19 pandemic, specifically in patients with hereditary arrhythmias, with emphasis on the congenital long QT syndrome (LQTS), Brugada syndrome (SBr), ventricular tachycardia polymorphic catecholaminergic (CPVT) and arrhythmogenic right ventricular cardiomyopathy.

摘要

自 2019 年 12 月以来，我们已经观察到由新型冠状病毒（SARS-CoV-2）引起的严重急性呼吸系统综合征的迅速发展。由于这些疾病的患病率较低，遗传性心律失常患者对呼吸道感染的临床过程知之甚少。由于发热、电解质紊乱、药物相互作用、肾上腺素能应激等多种因素，患有传染病的患者可能会使隐匿性或控制良好的原发性心律失常恶化，最终，脓毒症患者自身心肌损伤。本次综述的目的是强调我们在 COVID-19 大流行期间可能遇到的主要挑战，特别是在遗传性心律失常患者中，重点是先天性长 QT 综合征（LQTS）、Brugada 综合征（SBr）、多形性儿茶酚胺能室性心动过速（CPVT）和致心律失常性右心室心肌病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/f1b2ea196f98/0066-782X-abc-117-02-0394-gf04-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/10874be39ce8/0066-782X-abc-117-02-0394-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/d84d2403c58d/0066-782X-abc-117-02-0394-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/837ab63c63a9/0066-782X-abc-117-02-0394-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/c887c3d94dac/0066-782X-abc-117-02-0394-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/a54674dbbe70/0066-782X-abc-117-02-0394-gf01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/cb0cba87bcd2/0066-782X-abc-117-02-0394-gf02-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/a2a67d2e200d/0066-782X-abc-117-02-0394-gf03-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/f1b2ea196f98/0066-782X-abc-117-02-0394-gf04-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/10874be39ce8/0066-782X-abc-117-02-0394-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/d84d2403c58d/0066-782X-abc-117-02-0394-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/837ab63c63a9/0066-782X-abc-117-02-0394-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/c887c3d94dac/0066-782X-abc-117-02-0394-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/a54674dbbe70/0066-782X-abc-117-02-0394-gf01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/cb0cba87bcd2/0066-782X-abc-117-02-0394-gf02-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/a2a67d2e200d/0066-782X-abc-117-02-0394-gf03-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/8395786/f1b2ea196f98/0066-782X-abc-117-02-0394-gf04-en.jpg

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