Chatterjee S, Dey S K, Nag S K
Department of Physiology, University College of Science and Technology, Calcutta, India.
Jpn J Physiol. 1987;37(5):837-50. doi: 10.2170/jjphysiol.37.837.
Eighty-four healthy asymptomatic sedentary smokers and 92 healthy sedentary non-smokers of the age range 20-59 years were investigated for their maximum oxygen uptake capacity (VO2max) and related cardiorespiratory parameters at the level of maximal exercise by bicycle ergometry. The subjects were blocked into four age decades of 20-29, 30-39, 40-49, and 50-59 years to show the effect of smoking on VO2max of smokes of different age groups. The physical characteristics of smokers and non-smokers of comparable age groups did not show any significant difference. The smokers of each subsequent age group consumed 5.9 +/- 4.1, 6.3 +/- 5.7, 12.7 +/- 7.1, and 11.5 +/- 9.1 pack years of cigarettes, respectively (pack year = number of packets of cigarettes per day X number of years of smoking). VO2max of smokers (38.9 +/- 4.6 ml.kg-1.min-1) was significantly lower (p less than 0.05) than that of nonsmokers (42.1 +/- 3.2 ml.kg-1.min-1) only in the young age group of 20-29 years. VO2max expressed in per kg of the body weight (VO2max/BW) was found to be significantly (p less than 0.01) and negatively correlated with number of cigarettes smoked per day (-0.36, p less than 0.01), number of years through which smoked (-0.38, p less than 0.01), and pack years (-0.42, p less than 0.01). In other age groups, though non-smokers predominated over smokers in VO2max, the differences were not statistically significant. Also, in these age groups, smoking histories failed to reveal any significant correlation with VO2max. This suggests that smoking impairs VO2max only in the young ages. By increasing age, VO2max was diminished by 13% from 20 to 59 years in non-smokers and 15.5% from 20 to 59 years in smokers. Age also diminished HRmax and VEmax of smokers in the same manner as in the case of non-smokers. The VO2max of Indian sedentary non-smokers was found to be lower than those of Caucasians, Kurds, Yemenites, Europeans, and Africans. Values reported on Asians were found to be comparable with those of the present study.
对84名年龄在20 - 59岁之间、健康无症状的久坐吸烟者和92名健康久坐不吸烟者,通过自行车测力计在最大运动水平下研究他们的最大摄氧量(VO2max)及相关心肺参数。受试者被分为20 - 29岁、30 - 39岁、40 - 49岁和50 - 59岁这四个年龄段,以显示吸烟对不同年龄组吸烟者VO2max的影响。年龄相仿的吸烟者和不吸烟者的身体特征没有显著差异。随后各年龄组的吸烟者分别消耗了5.9±4.1、6.3±5.7、12.7±7.1和11.5±9.1包年的香烟(包年 = 每天吸烟包数×吸烟年数)。仅在20 - 29岁的年轻年龄组中,吸烟者的VO2max(38.9±4.6毫升·千克⁻¹·分钟⁻¹)显著低于(p<0.05)不吸烟者(42.1±3.2毫升·千克⁻¹·分钟⁻¹)。发现以每千克体重表示的VO2max(VO2max/BW)与每日吸烟量(-0.36,p<0.01)、吸烟年数(-0.38,p<0.01)和包年数(-0.42,p<0.01)显著(p<0.01)负相关。在其他年龄组中,虽然不吸烟者的VO2max高于吸烟者,但差异无统计学意义。此外,在这些年龄组中,吸烟史与VO2max未显示出任何显著相关性。这表明吸烟仅在年轻时会损害VO2max。随着年龄增长,不吸烟者的VO2max从20岁到59岁降低了13%,吸烟者降低了15.5%。年龄对吸烟者HRmax和VEmax的降低方式与不吸烟者相同。发现印度久坐不吸烟者的VO2max低于高加索人、库尔德人、也门人、欧洲人和非洲人。报道的亚洲人的数值与本研究的数值相当。