Chen Qi, Li Zheng, Pinho Ricardo A, Gupta Ramesh C, Ugbolue Ukadike C, Thirupathi Anand, Gu Yaodong
Faculty of Sports Science, Ningbo University, Ningbo, China.
Laboratory of Exercise Biochemistry in Health, Graduate Program in Health Sciences, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, Brazil.
Front Physiol. 2021 Aug 18;12:700352. doi: 10.3389/fphys.2021.700352. eCollection 2021.
Taurine is a naturally occurring amino acid involved in various functions, including regulating ion channels, cell volume, and membrane stabilization. However, how this molecule orchestrates such functions is unknown, particularly the dose response in exercised muscles. Therefore, this review aimed to systematically review the dose response of taurine on both aerobic and strength exercise performance. In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, relevant articles were sought on PubMed, Medline, Web of Science, and Google Scholar using related terms, including taurine, exercise performance, exercise, muscle, physical training, running, strength, endurance exercise, resistance exercise, aerobic exercise, and swimming. Ten articles were retrieved, reviewed, and subjected to systematic analysis. The following parameters were used to assess exercise performance in the selected studies: creatine kinase (CK), lactic acid dehydrogenase, carbohydrate, fat, glycerol, malondialdehyde, enzymatic antioxidants, blood pH, taurine level, and muscular strength. From the selected literature, we observed that taurine supplementation (2 g three times daily) with exercise can decrease DNA damage. Furthermore, 1 g of acute taurine administration before or after exercise can decrease lactate levels. However, acute administration of taurine (6 g) at a high dose before the start of exercise had no effect on reducing lactate level, but increased glycerol levels, suggesting that taurine could be an effective agent for prolonged activities, particularly at higher intensities. However, further studies are warranted to establish the role of taurine in fat metabolism during exercise. Finally, we observed that a low dose of taurine (0.05 g) before performing strength enhancing exercises can decrease muscular fatigue and increase enzymatic antioxidants. http://www.crd.york.ac.uk/PROSPERO, PROSPERO (CRD42021225243).
牛磺酸是一种天然存在的氨基酸，参与多种功能，包括调节离子通道、细胞体积和膜稳定性。然而，这种分子如何协调这些功能尚不清楚，特别是在运动肌肉中的剂量反应。因此，本综述旨在系统评价牛磺酸对有氧和力量运动表现的剂量反应。根据系统评价和Meta分析的首选报告项目（PRISMA）声明，在PubMed、Medline、科学网和谷歌学术上使用相关术语搜索相关文章，包括牛磺酸、运动表现、运动、肌肉、体育训练、跑步、力量、耐力运动、抗阻运动、有氧运动和游泳。检索到10篇文章，进行了综述并进行了系统分析。在所选研究中使用以下参数评估运动表现：肌酸激酶（CK）、乳酸脱氢酶、碳水化合物、脂肪、甘油、丙二醛、酶促抗氧化剂、血液pH值、牛磺酸水平和肌肉力量。从所选文献中，我们观察到运动时补充牛磺酸（每日3次，每次2克）可减少DNA损伤。此外，运动前或运动后急性给予1克牛磺酸可降低乳酸水平。然而，在运动开始前高剂量急性给予牛磺酸（6克）对降低乳酸水平没有影响，但会增加甘油水平，这表明牛磺酸可能是长时间活动的有效药物，特别是在较高强度时。然而，需要进一步研究以确定牛磺酸在运动期间脂肪代谢中的作用。最后，我们观察到在进行力量增强运动前低剂量给予牛磺酸（0.05克）可减少肌肉疲劳并增加酶促抗氧化剂。http://www.crd.york.ac.uk/PROSPERO，国际前瞻性系统评价注册库（CRD42021225243）。
