Faculty of Sports Science, Ningbo University, Ningbo 315211, China.
Savaria Institute of Technology, Eötvös Loránd University, Szombathely 9700, Hungary.
Biomed Res Int. 2021 Feb 11;2021:1947928. doi: 10.1155/2021/1947928. eCollection 2021.
Exercise-induced benefits are being increasingly recognized in promoting health and preventing diseases. However, initial adaption to exercise response can have different effects on cells, including an increase in the formation of oxidants and inflammatory mediators that ultimately leads to oxidative stress, but this scenario depends on the exercise type and intensity and training status of the individual. Therefore, we aimed to understand the effect of different types of exercise on oxidative stress. Indeed, exercise-induced minimum oxidative stress is required for regulating signaling pathways. According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, a search for relevant articles was carried out on PubMed/Medline, ISI Web of Science, and Google Scholar using a broad range of synonyms such as oxidants, reactive oxygen species (ROS), oxidative stress, exercise, physical training, aerobic exercise, and strength exercise until 2019. This study selected a total of 18 articles for assessing the oxidative damage using various parameters such as malondialdehyde (MDA), protein carbonyl (PCO), and F1-isoprostanes and enzymatic antioxidants. We observed that any type of exercise can increase the oxidative damage in an exercise type and intensity manner. Further, the training status of the individual and specific oxidative damage marker plays a crucial role in predicting earlier oxidative damage in the exercise condition. However, some of the studies that we included for review did not perform follow-up evaluations. Therefore, follow-up programs using larger numbers need to be performed to confirm our findings.
运动诱导的益处越来越被认可，有助于促进健康和预防疾病。然而，最初对运动反应的适应可能会对细胞产生不同的影响，包括氧化剂和炎症介质的形成增加，最终导致氧化应激，但这种情况取决于运动类型和强度以及个体的训练状态。因此，我们旨在了解不同类型的运动对氧化应激的影响。事实上，运动诱导的最小氧化应激对于调节信号通路是必需的。根据系统评价和荟萃分析的首选报告项目（PRISMA）声明，在 PubMed/Medline、ISI Web of Science 和 Google Scholar 上使用广泛的同义词（如氧化剂、活性氧物种（ROS）、氧化应激、运动、身体训练、有氧运动和力量训练）进行了相关文章的搜索，直到 2019 年。本研究共选择了 18 篇文章，使用各种参数评估氧化损伤，如丙二醛（MDA）、蛋白羰基（PCO）和 F1-异前列腺素以及酶抗氧化剂。我们观察到任何类型的运动都可以以运动类型和强度的方式增加氧化损伤。此外，个体的训练状态和特定的氧化损伤标志物在预测运动条件下的早期氧化损伤方面起着至关重要的作用。然而，我们纳入的一些研究没有进行后续评估。因此，需要进行更多随访评估的后续方案来证实我们的发现。
