Department of Food and Nutrition. School of Pharmaceutical Sciences of Araraquara. State University of São Paulo, Araraquara 14801-902, Brazil.
Faculty of Physical Education, State University of Minas Gerais, Divinopolis 35501-170, Brazil.
Nutrients. 2020 May 25;12(5):1540. doi: 10.3390/nu12051540.
Based on the fact that taurine can increase lipid metabolism, the objective of the present study was to evaluate the effects of different doses of acute taurine supplementation on lipid oxidation levels in healthy young men after a single bout of fasting aerobic exercise. A double-blind, acute, and crossover study design was conducted. Seventeen men (age 24.8 ± 4.07y; BMI: 23.9 ± 2.57 kg/m²) participated in the present study. Different doses of taurine (TAU) (3 g or 6 g) or placebo were supplemented 90 minutes before a single bout of fasting aerobic exercise (on a treadmill at 60% of VO2 max). The subjects performed three trials, and each one was separated by seven days. Blood samples were collected at baseline and after the exercise protocol of each test to analyze plasma levels of glycerol and taurine. Lipid and carbohydrate oxidation were determined immediately after exercise for 15 minutes by indirect calorimetry. We observed that TAU supplementation (6 g) increased lipid oxidation (38%) and reduced the respiratory coefficient (4%) when compared to the placebo ( < 0.05). However, no differences in lipid oxidation were observed between the different doses of taurine (3 g and 6 g). For glycerol concentrations, there were no differences between trials. Six grams of TAU supplementation 90 minutes before a single bout of aerobic exercise in a fasted state was sufficient to increase the lipid oxidation post-exercise in healthy young men.
基于牛磺酸可以增加脂肪代谢这一事实，本研究旨在评估单次禁食有氧运动后，不同剂量急性牛磺酸补充对健康年轻男性脂肪氧化水平的影响。采用双盲、急性、交叉设计进行研究。17 名男性（年龄 24.8 ± 4.07 岁；BMI：23.9 ± 2.57 kg/m²）参与了本研究。在单次禁食有氧运动（在跑步机上以 60%的最大摄氧量）前 90 分钟，受试者分别补充不同剂量的牛磺酸（TAU）（3 克或 6 克）或安慰剂。每个测试的三个试验之间相隔七天。在每个测试的运动方案后，采集血样以分析血浆甘油和牛磺酸水平。运动后立即通过间接测热法在 15 分钟内测定脂质和碳水化合物氧化。我们观察到，与安慰剂相比，TAU 补充（6 克）增加了 38%的脂肪氧化（<0.05）并降低了 4%的呼吸系数。然而，在不同剂量的牛磺酸（3 克和 6 克）之间，脂肪氧化没有差异。甘油浓度在试验之间没有差异。在禁食状态下单次有氧运动前 90 分钟补充 6 克 TAU 足以增加健康年轻男性运动后的脂肪氧化。
