Yoshitomi Kasumi Kaneko, Numao Noboru, Umino Yosuke, Fujiwara Motohiro, Fujiwara Ryo, Oguchi Tomohiko, Komai Yoshinobu, Yuasa Takeshi, Yamamoto Shinya, Yonese Junji
Department of Urology Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.
Department of Urology Showa General Hospital Tokyo Japan.
IJU Case Rep. 2021 Jun 16;4(5):285-288. doi: 10.1002/iju5.12327. eCollection 2021 Sep.
Although the utility of diffusion-weighted whole-body imaging with background body signal suppression for assessing lymph node involvement or distant metastasis is renowned in many cancers, only few studies have revealed its utility for germ cell carcinoma. Some metastatic lesions of germ cell carcinomas are difficult to detect by conventional imaging.
We report a case of a 70-year-old man with relapsed retroperitoneal germ cell tumor. Although his human chorionic gonadotropin levels increased, conventional imaging analysis showed no evidence of recurrence. Diffusion-weighted whole-body imaging with background body signal suppression was performed to search the metastatic lesion and detected metastatic sacral lesions. The patient responded well to local radiotherapy added to the steroid pulse and salvage chemotherapy and achieved long-term recurrence-free survival.
Diffusion-weighted whole-body imaging with background body signal suppression has the potential to detect metastatic lesions not usually detected by conventional imaging methods.
尽管背景体部信号抑制的扩散加权全身成像在评估许多癌症的淋巴结受累或远处转移方面的效用广为人知，但仅有少数研究揭示了其在生殖细胞癌中的效用。生殖细胞癌的一些转移病灶难以通过传统成像检测到。
我们报告一例70岁复发性腹膜后生殖细胞肿瘤男性患者。尽管其血清人绒毛膜促性腺激素水平升高，但传统成像分析未显示复发迹象。进行背景体部信号抑制的扩散加权全身成像以寻找转移病灶，并检测到骶骨转移病灶。该患者对加用类固醇脉冲和挽救性化疗的局部放疗反应良好，并实现了长期无复发生存。
背景体部信号抑制的扩散加权全身成像有潜力检测出通常无法通过传统成像方法检测到的转移病灶。
