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物种中的植物化学物质:在抗氧化、抗炎、抗癌和化学预防活性方面的潜力和意义。

Phytochemicals from Species: Potential and Implication on Anti-Oxidant, Anti-Inflammatory, Anti-Cancer, and Chemoprevention Activities.

机构信息

Department of Anatomy, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.

Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.

出版信息

Molecules. 2021 Sep 3;26(17):5369. doi: 10.3390/molecules26175369.

Abstract

belong to the Annonaceae family and are a type of evergreen tree distributed across many tropical and subtropical regions. species have been used long term as indigenous medicine to treat certain diseases, including fever, diabetes, infection, digestive disease, etc. Recent studies have demonstrated that not only crude extracts but also the isolated pure compounds exhibit various pharmacological activities, such as anti-oxidant, anti-microbial, anti-tumor, anti-cancer, etc. It is known that the initiation of cancer usually takes several years and is related to unhealthy lifestyle, as well as dietary and environmental factors, such as stress, toxins and smoking. In fact, natural or synthetic substances have been used as cancer chemoprevention to delay, impede, or even stop cancer growing. This review is an attempt to collect current available phytochemicals from , which exhibit anti-cancer potentials for chemoprevention purposes, providing directions for further research on the interesting agents and possible clinical applications.

摘要

属于番荔枝科,是一种分布在许多热带和亚热带地区的常绿乔木。长期以来,该属的一些种被用作传统药物来治疗某些疾病,包括发热、糖尿病、感染、消化疾病等。最近的研究表明,不仅粗提取物,而且分离的纯化合物也表现出多种药理活性,如抗氧化、抗菌、抗肿瘤、抗癌等。众所周知,癌症的发生通常需要几年的时间,与不健康的生活方式以及饮食和环境因素有关,如压力、毒素和吸烟。事实上,天然或合成物质已被用作癌症化学预防剂,以延缓、阻碍甚至阻止癌症的生长。本综述试图收集目前可从 中获得的具有抗癌潜力的植物化学物质,为进一步研究这些有趣的药物和可能的临床应用提供方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e60a/8433920/b95f19eb0a9b/molecules-26-05369-g001.jpg

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