重症监护后综合征及其在2019冠状病毒病（COVID-19）大流行中的新挑战：近期进展与展望综述
Post-Intensive Care Syndrome and Its New Challenges in Coronavirus Disease 2019 (COVID-19) Pandemic: A Review of Recent Advances and Perspectives.
作者信息
Nakanishi Nobuto, Liu Keibun, Kawakami Daisuke, Kawai Yusuke, Morisawa Tomoyuki, Nishida Takeshi, Sumita Hidenori, Unoki Takeshi, Hifumi Toru, Iida Yuki, Katsukawa Hajime, Nakamura Kensuke, Ohshimo Shinichiro, Hatakeyama Junji, Inoue Shigeaki, Nishida Osamu
机构信息
Department of Disaster and Emergency Medicine, Graduate School of Medicine, Kobe University, 7-5-2, Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Critical Care Research Group, Faculty of Medicine, University of Queensland and The Prince Charles Hospital, 627 Rode Rd, Chermside, Brisbane, QLD 4032, Australia.
出版信息
J Clin Med. 2021 Aug 28;10(17):3870. doi: 10.3390/jcm10173870.
Intensive care unit survivors experience prolonged physical impairments, cognitive impairments, and mental health problems, commonly referred to as post-intensive care syndrome (PICS). Previous studies reported the prevalence, assessment, and prevention of PICS, including the ABCDEF bundle approach. Although the management of PICS has been advanced, the outbreak of coronavirus disease 2019 (COVID-19) posed an additional challenge to PICS. The prevalence of PICS after COVID-19 extensively varied with 28-87% of cases pertaining to physical impairments, 20-57% pertaining to cognitive impairments, and 6-60% pertaining to mental health problems after 1-6 months after discharge. Each component of the ABCDEF bundle is not sufficiently provided from 16% to 52% owing to the highly transmissible nature of the virus. However, new data are emerging about analgesia, sedation, delirium care, nursing care, early mobilization, nutrition, and family support. In this review, we summarize the recent data on PICS and its new challenge in PICS after COVID-19 infection.
重症监护病房幸存者会经历长期的身体损伤、认知障碍和心理健康问题，通常被称为重症监护后综合征（PICS）。以往的研究报告了PICS的患病率、评估和预防，包括ABCDEF集束化方案。尽管PICS的管理已经取得进展，但2019冠状病毒病（COVID-19）的爆发给PICS带来了额外挑战。COVID-19后PICS的患病率差异很大，出院后1至6个月，28%-87%的病例存在身体损伤，20%-57%存在认知障碍，6%-60%存在心理健康问题。由于病毒的高传播性，ABCDEF集束化方案的每个组成部分有16%至52%未得到充分实施。然而，关于镇痛、镇静、谵妄护理、护理、早期活动、营养和家庭支持的新数据正在不断涌现。在本综述中，我们总结了近期关于PICS及其在COVID-19感染后PICS中面临的新挑战的数据。
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