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女性尿道成形术:单中心不同技术的治疗结果

Female Urethroplasty: Outcomes of Different Techniques in a Single Center.

作者信息

Waterloos Marjan, Verla Wesley, Wirtz Michel, Waterschoot Mieke, Claeys Wietse, Francois Philippe, Lumen Nicolaas

机构信息

AZ Maria Middelares Gent, 9000 Ghent, Belgium.

Ghent University Hospital, 9000 Ghent, Belgium.

出版信息

J Clin Med. 2021 Aug 31;10(17):3950. doi: 10.3390/jcm10173950.

Abstract

INTRODUCTION

Female urethral strictures and injuries are relatively uncommon compared to males. A wide range of possible causes and treatment modalities have been described. Lately female urethral reconstruction is gaining attention and is fortunately no longer a neglected topic within the reconstructive urology. As such, we aimed to describe our surgical techniques and outcomes for female urethroplasty from a tertiary center.

MATERIALS AND METHODS

Records of female patients who underwent a urethroplasty between July 2018 and May 2021 in our tertiary referral center were reviewed. Patients were subdivided in two groups: patients who suffered from a urethral injury and received an early repair urethroplasty, and patients with a true urethral stricture who received a delayed urethroplasty. Preprocedural, surgical and postoperative data were collected and analyzed with descriptive statistics.

RESULTS

A total of five patients in group 1 and nine patients in group 2 were included. Etiology of the urethral injury in group 1 was iatrogenic in 80% and transitional cell carcinoma of the urethra in 20% of cases. A patency rate of 100% at a follow-up of 30 months was achieved with the different techniques. In group 2 etiology was idiopathic (44%), iatrogenic (44%) and due to external trauma in 12% of cases. Urethroplasty technique consisted of primary repair or dorsal onlay of a buccal mucosal graft. Patency rate was 100% at a median follow-up of 13 months. Three patients suffered from postoperative urinary incontinence, one in group 1 and two in group 2.

CONCLUSION

Female urethroplasty is a relatively rare entity within reconstructive urethral surgery. This case series of 14 patients demonstrates that with appropriate surgical techniques, a high patency rate with a low complication rate can be achieved. Further prospective studies with standardized diagnostic workup and follow-up should be performed in order to optimize management strategy.

摘要

引言

与男性相比,女性尿道狭窄和损伤相对少见。已有多种可能的病因和治疗方式被描述。近来,女性尿道重建受到关注,幸运的是,它在重建泌尿外科领域不再是一个被忽视的话题。因此,我们旨在描述我们三级中心女性尿道成形术的手术技术和结果。

材料与方法

回顾了2018年7月至2021年5月在我们三级转诊中心接受尿道成形术的女性患者记录。患者分为两组:遭受尿道损伤并接受早期修复尿道成形术的患者,以及患有真性尿道狭窄并接受延迟尿道成形术的患者。收集术前、手术和术后数据,并进行描述性统计分析。

结果

第1组共纳入5例患者,第2组共纳入9例患者。第1组尿道损伤的病因80%为医源性,20%为尿道移行细胞癌。采用不同技术在30个月随访时通畅率达到100%。第2组病因中,特发性占44%,医源性占44%,12%为外部创伤。尿道成形术技术包括一期修复或颊黏膜移植片背侧覆盖。在中位随访13个月时通畅率为100%。3例患者出现术后尿失禁,第1组1例,第2组2例。

结论

女性尿道成形术在重建尿道手术中是一种相对罕见的情况。这个14例患者的病例系列表明,采用适当的手术技术,可以实现高通畅率和低并发症率。应进行进一步的前瞻性研究,采用标准化的诊断检查和随访,以优化管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3101/8432057/404e2061f18e/jcm-10-03950-g001.jpg

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