Department of Dermatology, Venereology and Pediatric Dermatology, Medical University of Lublin, Staszica 11 St., 20-081 Lublin, Poland.
Department of Cosmetology and Aesthetic Medicine, Medical University of Lublin, Chodźki 1 St., 20-093 Lublin, Poland.
Sensors (Basel). 2021 Sep 6;21(17):5981. doi: 10.3390/s21175981.
Eyebrow loss in the course of frontal fibrosing alopecia (FFA) is becoming a growing issue among older females. It has a considerable negative impact on patients' quality of life. Since there is no standardized treatment, photobiomodulation with light-emitting diodes (LEDs) could be an option. Here we assess, for the first time, the efficacy of LED therapy in the treatment of eyebrow loss in females with FFA.
16 female patients with FFA aged 60-74 years were enrolled in the study. LED therapy was performed once a week for a 10-week session. The LEDs' effectiveness was assessed at the baseline, after 10 irradiations, and 6 months after the end of treatment during a follow-up visit.
The therapy was well tolerated. After 10 irradiations, the total eyebrow hair count increased significantly, as did the number of thick hairs and mid-thick hairs ( = 0.002, = 0.002, and = 0.044, respectively). During the follow-up visit, the total number of eyebrow hairs remained significantly higher than before treatment ( = 0.002).
The study revealed that LED therapy seems to be a novel and promising therapeutic option for eyebrow loss in patients with FFA. It is safe and well tolerated and leads to clinically and cosmetically acceptable improvement.
在额部纤维性脱发（FFA）过程中眉毛脱落，成为老年女性日益关注的问题。它对患者的生活质量有很大的负面影响。由于没有标准化的治疗方法，发光二极管（LED）的光生物调节可能是一种选择。在这里，我们首次评估了 LED 疗法治疗 FFA 女性眉毛缺失的疗效。
16 名 60-74 岁患有 FFA 的女性患者入组本研究。每周进行一次 LED 治疗，共 10 次。在基线、10 次照射后和治疗结束后 6 个月的随访期间评估 LED 治疗的有效性。
治疗耐受性良好。10 次照射后，总眉毛毛发计数显著增加，粗毛和中粗毛数量也显著增加（分别为 = 0.002、 = 0.002 和 = 0.044）。随访时，眉毛毛发总数仍明显高于治疗前（ = 0.002）。
研究表明，LED 疗法似乎是 FFA 患者眉毛缺失的一种新颖且有前途的治疗选择。它安全且耐受性良好，可带来临床和美容上可接受的改善。
