Cardiovascular Medicine Department, SUNY Stony Brook Medicine, Stony Brook, NY, USA.
Division of Internal Medicine, Bronx Care Hospital Center, Bronx, NY, USA.
Curr Cardiol Rev. 2022;18(3):e090921196330. doi: 10.2174/1573403X17666210909170415.
Heart failure is one of the leading healthcare problems in the world. Clinical data lacks sensitivity and specificity in the diagnosis of heart failure. Laboratory biomarkers are a non-invasive method of assessing suspected decompensated heart failure. Biomarkers such as natriuretic peptides have shown promising results in the management of heart failure. The literature does not provide comprehensive guidance in the utilization of biomarkers in the setting of acute heart failure syndrome. Many conditions that manifest with similar pathophysiology as acute heart failure syndrome may demonstrate positive biomarkers. The following is a review of biomarkers in heart failure, enlightening their role in diagnosis, prognosis and management of heart failure.
心力衰竭是世界范围内主要的医疗保健问题之一。临床数据在心力衰竭的诊断中缺乏敏感性和特异性。实验室生物标志物是评估疑似心力衰竭失代偿的一种非侵入性方法。生物标志物,如利钠肽,在心衰管理中显示出有前景的结果。文献并没有在急性心力衰竭综合征的背景下提供生物标志物使用的全面指导。许多表现出与急性心力衰竭综合征相似病理生理学的病症可能显示出阳性生物标志物。以下是对心力衰竭生物标志物的综述,阐明了它们在心衰的诊断、预后和管理中的作用。