Center for Interdisciplinary Research in Biology, Collège de France, UMR7241/U1050, Paris Sciences et Lettres Research University, Paris, France.
J Cell Biol. 2021 Oct 4;220(10). doi: 10.1083/jcb.202108030. Epub 2021 Sep 10.
Fertilization often triggers the final step of haploidization of the female gamete genome. In this issue, Mori et al. (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202012001) identify two successive actin-dependent mechanisms that delay fusion of maternal and paternal chromosomes, preventing inadvertent elimination of paternal chromosomes together with maternal ones.
受精通常会引发雌性配子基因组单倍体化的最后一步。在本期中，Mori 等人（2021.《细胞生物学杂志》https://doi.org/10.1083/jcb.202012001）确定了两个连续的肌动蛋白依赖性机制，它们延迟了母本和父本染色体的融合，防止了父本染色体与母本染色体一起被意外消除。
