Department of Clinical Oncology, Bir Hospital, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2021 Jan 31;59(233):81-83. doi: 10.31729/jnma.5591.
The systemic lupus erythematosus (SLE) is a connective tissue disorder with variable presentations in children. The usual presentation includes arthritis, malar rash, nephritis, hemolytic anemia, and fever. Isolated hematologic abnormality as the only presentation of SLE is rare. Here is a case report of a female child presented to us with superficial and mucosal bleeding with isolated low platelet count and anemia in proportion to blood loss. When platelet count did not go up despite appropriate treatment in lines of ITP, further investigations were done, diagnosis of SLE was established, and management was done accordingly.
系统性红斑狼疮（SLE）是一种结缔组织疾病，在儿童中有多种表现。常见的表现包括关节炎、蝶形红斑、肾炎、溶血性贫血和发热。孤立的血液学异常作为 SLE 的唯一表现较为少见。这里报告一例女性患儿，以单纯血小板计数降低和与失血成比例的贫血为表现，伴有皮肤黏膜出血。尽管按照 ITP 的治疗方案进行了适当的治疗，但血小板计数仍未升高，进一步的检查发现，诊断为 SLE，并进行了相应的治疗。
