Department of Internal Medicine, Scheer Memorial Adventist Hospital, Banepa, Kavrepalanchok, Nepal.
Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2021 Aug 12;59(240):805-807. doi: 10.31729/jnma.6454.
Nepal started the COVID-19 vaccination on 27 January 2021 with AstraZeneca/Oxford Coronavirus Disease-19 AZD1222 (Covishield) vaccine to control the Coronavirus disease pandemic. The vaccine has a good safety profile, with cardiovascular complications being rare. Herein we report a rare case of cardiovascular complication following Covishield vaccination in a 33 years old female who had dizziness and elevated blood pressure immediately following vaccination and abnormal electrocardiogram showing T wave inversions followed by left bundle branch block. The patient was kept on observation, following which the blood pressure and electrocardiogram changes were normal by seven days. This cardiovascular complication following the vaccination demands further investigation into the adverse event of the vaccine. However, since the benefit of the vaccine outweighs the risk, World Health Organization has recommended the continuity of the vaccine as of now.
尼泊尔于 2021 年 1 月 27 日开始使用阿斯利康/牛津 COVID-19 疫苗(Covishield)来控制冠状病毒病大流行。该疫苗具有良好的安全性,心血管并发症罕见。在此,我们报告了一例接种 Covishield 疫苗后出现心血管并发症的罕见病例,一名 33 岁女性在接种疫苗后立即出现头晕和血压升高,心电图显示 T 波倒置,随后出现左束支传导阻滞。患者接受了观察,七天后血压和心电图变化恢复正常。这种接种疫苗后的心血管并发症需要进一步调查疫苗的不良反应。然而,由于疫苗的益处大于风险,世界卫生组织建议继续使用该疫苗。