Kubasiewicz M, Starzyński Z
Instytutu Medycyny Pracy im. prof. dra med. Jerzego Nofera w Lodzi.
Med Pr. 1987;38(6):441-6.
The paper deals with the effects of occupational environment on the skin cancer prevalence rates. Particularly, the impact of polycyclic aromatic hydrocarbons (PAHs) has been enhanced. Due to the long latency between the initial contact with PAH-emitting substances (asphalt, tar, oils, soot) and cancer occurrence, and also due to the usually advanced age of affected workers, the evaluation of chemical carcinogens in skin cancer prevalence is hampered and so imprecise. On the other hand, the PAH-exposure in the working environment is considerable and scattered; the most skin cancer- affected population is not covered by occupational health service because of their advanced age. A reliable determination of the cancer risk in workers exposed to PAHs during their professionally active life would call for an epidemiological study with an appropriate selection of reference groups allowing for elimination of the factors modifying and disturbing the issue concerned. Such a study has been undertaken at the Institute of Occupational Medicine in Lódź.
本文探讨职业环境对皮肤癌患病率的影响。特别是,多环芳烃(PAHs)的影响已得到强化。由于首次接触释放PAH的物质(沥青、焦油、油类、烟尘)与癌症发生之间存在较长的潜伏期,且受影响工人通常年龄较大,因此在皮肤癌患病率中对化学致癌物的评估受到阻碍且不够精确。另一方面,工作环境中的PAH暴露量很大且分布分散;大多数受皮肤癌影响的人群因年龄较大而未被职业健康服务所覆盖。要可靠地确定在职业活动期间接触PAHs的工人患癌风险,就需要进行一项流行病学研究,适当选择参照组,以便消除影响和干扰相关问题的因素。罗兹职业医学研究所已开展了这样一项研究。