Department of Internal Medicine, Gza Hospitals, Antwerp, Belgium.
Department of Paediatrics, Gza Hospitals, Antwerp, Belgium.
Acta Clin Belg. 2022 Aug;77(4):772-777. doi: 10.1080/17843286.2021.1977899. Epub 2021 Sep 12.
We discuss a case of a young woman, presenting a constellation of clinical and biochemical features meeting the current case definition of multisystem inflammatory syndrome in adults (MIS-A), 18 days after receiving her first dose of the Oxford/AstraZeneca vaccine. Therapy by means of intravenous immunoglobulins was initiated, leading to clinical and biochemical recovery. Although a relationship between MIS-A and the preceding vaccination cannot be confirmed, it can also not be excluded, given the temporal association and the fact that there were no indicators of a preceding SARS-CoV-2 infection.
我们讨论了一例年轻女性的病例,她在接种第一剂牛津/阿斯利康疫苗 18 天后出现了一系列符合成人多系统炎症综合征(MIS-A)当前病例定义的临床和生化特征。通过静脉注射免疫球蛋白进行治疗,导致临床和生化恢复。尽管无法确认 MIS-A 与先前的疫苗接种之间存在关联,但鉴于时间上的关联以及没有 SARS-CoV-2 感染前期指标的事实,也不能排除这种关联。