Division of Hospital Medicine, Department of Medicine, Warren Alpert Medical School at Brown University, Providence, Rhode Island, USA
Division of Hospital Medicine, Department of Medicine, Warren Alpert Medical School at Brown University, Providence, Rhode Island, USA.
BMJ Case Rep. 2022 Apr 26;15(4):e249425. doi: 10.1136/bcr-2022-249425.
The ability of SARS-CoV-2 to trigger hyperinflammatory response in children and adults is increasingly recognised. However, the detailed features that distinguish severe COVID-19-associated hyperinflammation from multisystem inflammatory syndrome in adults (MIS-A) is not yet known. We describe a young, vaccinated patient with no prior SARS-CoV-2 exposure who developed COVID-19 and MIS-A. We also provide a review of the current literature on MIS-A and COVID-19-associated hyperinflammation.
越来越多的人认识到,SARS-CoV-2 能够引发儿童和成人的过度炎症反应。然而,严重 COVID-19 相关过度炎症与成人多系统炎症综合征(MIS-A)之间的具体区别尚不清楚。我们描述了一名年轻、接种过疫苗的患者,他没有 SARS-CoV-2 接触史,却发展为 COVID-19 和 MIS-A。我们还对目前关于 MIS-A 和 COVID-19 相关过度炎症的文献进行了回顾。