LSU Health Shreveport, 1501 Kings Highway, Shreveport LA 71103, USA.
Department of Anesthesiology, LSU Health Shreveport, 1501 Kings Highway, Shreveport LA 71103, USA.
Best Pract Res Clin Anaesthesiol. 2021 Oct;35(3):269-292. doi: 10.1016/j.bpa.2020.12.003. Epub 2020 Dec 8.
Coronaviruses belong to the family Coronaviridae order Nidovirales and are known causes of respiratory and intestinal disease in various mammalian and avian species. Species of coronaviruses known to infect humans are referred to as human coronaviruses (HCoVs). While traditionally, HCoVs have been a significant cause of the common cold, more recently, emergent viruses, including severe acute respiratory syndrome coronavirus (SARS-CoV-2) has caused a global pandemic. Here, we discuss coronavirus disease (COVID-19) biology, pathology, epidemiology, signs and symptoms, diagnosis, treatment, and recent clinical trials involving promising treatments.
冠状病毒属于冠状病毒科、套式病毒目，已知可引起多种哺乳动物和禽类的呼吸道和肠道疾病。已知感染人类的冠状病毒被称为人类冠状病毒（HCoV）。虽然传统上 HCoV 是普通感冒的重要病因，但最近出现的新型冠状病毒，包括严重急性呼吸综合征冠状病毒（SARS-CoV-2），已导致全球大流行。在此，我们讨论了冠状病毒病（COVID-19）的生物学、病理学、流行病学、体征和症状、诊断、治疗以及涉及有前途治疗方法的最新临床试验。
