在暴露于不同光周期条件下的去势雄性仓鼠中，垂体对促黄体释放因子（LRF）的反应性。
Pituitary responsiveness to LRF in castrated male hamsters exposed to different photoperiodic conditions.
作者信息
Turek F W, Alvis J D, Menaker M
出版信息
Neuroendocrinology. 1977;24(3-4):140-6. doi: 10.1159/000122705.
The effect of various doses of LRF on pituitary LH and FSH release was examined in castrated adult male hamsters with different photoperiodic histories. Gonadotropin (Gn) release in response to LRF was independent of whether the animals had been exposed to a photostimulatory (LD 14:10) or a nonstimulatory (LD 6:18) light cycle for 60 days following castration. The lowest dose that caused a significant increase in serum Gns was 10 ng LRF/100 g b.w. for LH and 50 ng LRF/100 g b.w. for FSH. These results indicate that photoperiod, which is well known to exert major effects on the reproductive system of the golden hamster, does not do so by directly altering the responsiveness of the pituitary gland to hypothalamic Gn-releasing factor.
在具有不同光照周期经历的去势成年雄性仓鼠中，研究了不同剂量的促黄体生成素释放因子（LRF）对垂体促黄体生成素（LH）和促卵泡生成素（FSH）释放的影响。促性腺激素（Gn）对LRF的反应与动物在去势后60天是暴露于光刺激（14小时光照：10小时黑暗）还是非刺激（6小时光照：18小时黑暗）光周期无关。引起血清Gn显著增加的最低剂量，LH为10 ng LRF/100 g体重，FSH为50 ng LRF/100 g体重。这些结果表明，众所周知，光照周期对金黄仓鼠的生殖系统有重大影响，但它并非通过直接改变垂体对下丘脑Gn释放因子的反应性来实现这一点。
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