Department of Laboratory Medicine and Pathology, Hamad Medical Corporation, DOHA, QATAR.
Turk Patoloji Derg. 2022;38(2):153-157. doi: 10.5146/tjpath.2021.01543.
Pleomorphic adenoma of breast (PAB) is a rare mammary tumor of a mixed epithelial-myoepithelial nature. We report two patients with PAB, one of which is male. We believe our male patient is the sixth case of PAB in male breast in the literature. The two cases expressed heterogeneous clinical and radiological characteristics while showing similar histology and immunohistochemical staining profile. The first case was managed with surgical resection while the second underwent interventional radiology excision. PAB is usually a benign entity with occasional cases of recurrence. Malignant transformation is rare but has been reported in a few cases.
乳腺多形性腺瘤(PAB)是一种罕见的混合上皮-肌上皮性质的乳腺肿瘤。我们报告了两例 PAB 患者,其中一例为男性。我们认为我们的男性患者是文献中第六例男性乳腺 PAB 病例。这两个病例表现出不同的临床和影像学特征,同时表现出相似的组织学和免疫组织化学染色特征。第一例采用手术切除治疗,第二例采用介入放射学切除。PAB 通常是一种良性实体瘤,偶尔会有复发的情况。恶性转化很少见,但已有少数病例报道。