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甲状腺恶性肿瘤手术的术中神经监测:技术要点及回顾性系列研究结果

Intraoperative neuromonitoring for thyroid malignancy surgery: technical notes and results from a retrospective series.

作者信息

Frattini Francesco, Mangano Alberto, Boni Luigi, Rausei Stefano, Biondi Antonio, Dionigi Gianlorenzo

机构信息

Department of Surgical Sciences, Endocrine Surgery Research Center, University of Insubria (Varese-Como), Via Guicciardini, 21100, Varese, Italy.

出版信息

Updates Surg. 2010 Dec;62(3-4):183-7. doi: 10.1007/s13304-010-0036-5.

Abstract

This study evaluates the role of intraoperative neuromonitoring (IONM) for thyroidectomy performed in cancer patients with emphasis on postoperative recurrent laryngeal nerve paralysis (RLNP). The study is a retrospective series comprising 76 thyroidectomy alone (control group) versus 76 thyroidectomy with IONM. In the control group the laryngeal nerves have been identified by visualization solely. In the IONM group both vagal nerve and RLN have been localized and monitored during thyroid resection. The main surgical outcome was RLN morbidity. All patients undergo pre- and postoperative laryngeal examination. Overall RLN morbidity was 3.9% in the IONM group and 9.2% in the control group (P < 0.05). There have been two cases of permanent RLNP (2.6%) in the control group and one in the IONM group (1.3%), one case of bilateral RLN injury in the control group. The incidences of temporary RLNP in the IONM group have been 2.6 versus 6.5% in the control group. IONM is an effective procedure in thyroid cancer patients.

摘要

本研究评估术中神经监测(IONM)在癌症患者甲状腺切除术中的作用,重点关注术后喉返神经麻痹(RLNP)。该研究是一项回顾性系列研究,包括76例单纯甲状腺切除术(对照组)和76例接受IONM的甲状腺切除术。在对照组中,仅通过可视化识别喉神经。在IONM组中,在甲状腺切除期间对迷走神经和喉返神经进行定位和监测。主要手术结果是喉返神经发病率。所有患者均接受术前和术后喉部检查。IONM组的总体喉返神经发病率为3.9%,对照组为9.2%(P<0.05)。对照组有2例永久性RLNP(2.6%),IONM组有1例(1.3%),对照组有1例双侧喉返神经损伤。IONM组的暂时性RLNP发生率为2.6%,而对照组为6.5%。IONM在甲状腺癌患者中是一种有效的方法。

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