Sidhom Fady, Sandhu Harminder
Internal Medicine, Howard University Hospital, Washington, USA.
Cureus. 2021 Aug 10;13(8):e17052. doi: 10.7759/cureus.17052. eCollection 2021 Aug.
Since the identification of SARS-CoV-2 or COVID-19 in Wuhan, several case reports have proposed a possible association between Guillain-Barre syndrome (GBS) and COVID-19. We describe a case of a 59-year-old female who initially presented with shortness of breath, tested positive for COVID-19, and subsequently developed acute hypoxic respiratory failure requiring mechanical ventilation. Her recovery was complicated by acute polyneuropathy. Clinical exam and lumbar puncture showing an albuminocytologic dissociation were consistent with GBS. The prevalence and association of GBS following COVID-19 infection require further research to understand the short and long-term neurological effects of COVID-19, as well as the management of these various neurological manifestations.
自武汉发现严重急性呼吸综合征冠状病毒2(SARS-CoV-2)或新型冠状病毒肺炎(COVID-19)以来,已有数例病例报告提出吉兰-巴雷综合征(GBS)与COVID-19之间可能存在关联。我们报告一例59岁女性病例,该患者最初表现为呼吸急促,COVID-19检测呈阳性,随后发展为需要机械通气的急性低氧性呼吸衰竭。她的康复过程因急性多发性神经病而复杂化。临床检查和腰椎穿刺显示蛋白细胞分离,与GBS相符。COVID-19感染后GBS的患病率和关联性需要进一步研究,以了解COVID-19的短期和长期神经影响,以及这些各种神经表现的管理。