Archana T S, Shetty Akshay, Imran Mohammed, Ahmed Nida, Kumar Praveen, Shruthi T M
Department of Oral and Maxillofacial Surgery, AECS Maaruti College of Dental Sciences and Research Center, Bengaluru, Karnataka, India.
Department of Oral and Maxillofacial Surgery, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Bengaluru, Karnataka, India.
Ann Maxillofac Surg. 2021 Jan-Jun;11(1):156-159. doi: 10.4103/ams.ams_334_20. Epub 2021 Jul 24.
Undifferentiated pleomorphic sarcoma originally known as malignant fibrous histiocytoma was declassified by the World Health Organization in 2002 as a formal diagnostic entity and renamed as an undifferentiated pleomorphic sarcoma. It accounts for <1% of malignant tumours of the long bone.
A 33-year-old male patient reported with swelling and pain in the lower left posterior jaw region for 3 months with a history of fall on the floor 3 months back.
On examination, diffuse solitary swelling was present on the left lower third of the face and was diagnosed radiographically and histopathologically as undifferentiated pleomorphic sarcoma of the mandible.
Selective neck dissection, followed by reconstruction with fibula osteomyocutaneous flap and then referred for adjuvant radiotherapy.
TAKE-AWAY LESSONS: Vimentin staining plays a substantial role in the diagnosis of undifferentiated pleomorphic sarcoma. A long-term follow-up after treatment is required to increase the chances of disease-free survival for the patients.
未分化多形性肉瘤最初被称为恶性纤维组织细胞瘤，2002年世界卫生组织将其从正式诊断实体中除名，并重新命名为未分化多形性肉瘤。它占长骨恶性肿瘤的比例不到1%。
一名33岁男性患者报告左下后颌区域肿胀疼痛3个月，3个月前有摔倒在地的病史。
检查发现左侧面部下三分之一处有弥漫性孤立肿胀，经影像学和组织病理学诊断为下颌骨未分化多形性肉瘤。
进行选择性颈清扫术，随后用腓骨骨肌皮瓣进行重建，然后接受辅助放疗。
波形蛋白染色在未分化多形性肉瘤的诊断中起重要作用。治疗后需要长期随访以增加患者无病生存的机会。
