Cao G R, English P B, Filippich L J, Inglis S
Department of Veterinary Medicine, University of Queensland, St Lucia.
Aust Vet J. 1987 Dec;64(12):367-70. doi: 10.1111/j.1751-0813.1987.tb09605.x.
Lactic acidosis was produced experimentally twice in each of 4 adult, female goats, by giving sucrose orally at the rate of 18 g/kg bodyweight. Changes in pH, osmolality, lactic acid concentration, and other constituents in ruminal fluid, plasma and blood were monitored over a period of 48 h. Also changes in urinary pH and sediment were examined. To ameliorate the metabolic disturbance, calcium hydroxide and bicarbonate treatment was employed after the 24 h samples had been collected and their acid-base status determined. A feature of the disturbance in the goats was that a metabolic alkalosis preceded the onset of lactic acidosis.