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婴儿湿巾与尿布疹——它们之间有何关系?一篇综述。

Baby wipes and nappy rash - what is the relationship? A review.

机构信息

University of Melbourne, Melbourne, VIC, Australia.

Department of Dermatology, Royal Children's Hospital, Parkville, VIC, Australia.

出版信息

Australas J Dermatol. 2021 Nov;62(4):470-477. doi: 10.1111/ajd.13715. Epub 2021 Sep 15.

DOI:10.1111/ajd.13715
PMID:34523734
Abstract

Baby wipes are a commonly used cleansing method for infants. A literature review has been performed to assess if using baby wipes is beneficial or harmful compared to water and cloth in terms of nappy rash. This includes a detailed analysis of baby wipe ingredients, as many skin irritants as well as allergens are identified. MedLine, Embase and PubMed were searched and after 420 titles and abstracts were screened, 21 studies remained for inclusion. Baby wipes are deemed as superior to water and cloth in the majority of the literature. However, no definitive conclusion can be drawn as many studies are also industry funded. The most notable allergens identified are fragrances, such as linalool, cocamidopropyl betaine (surfactant), formaldehyde-releasing preservatives and other preservatives, including methylisothiazolinone and methylchloroisothiazolinone. As not all allergens are listed on the label accurately, this can be misleading for the consumer.

摘要

婴儿湿巾是一种常用的婴儿清洁方法。为了评估与水和布相比,使用婴儿湿巾在尿布疹方面是有益还是有害,我们进行了文献综述。这包括对婴儿湿巾成分的详细分析,因为许多皮肤刺激物和过敏原都已被确定。我们检索了 MedLine、Embase 和 PubMed,并在筛选了 420 个标题和摘要后,有 21 项研究被纳入。在大多数文献中,婴儿湿巾被认为优于水和布。然而,由于许多研究也得到了行业的资助,因此无法得出明确的结论。已确定的最显著的过敏原是香料,如芳樟醇、椰油酰胺丙基甜菜碱(表面活性剂)、释放甲醛的防腐剂和其他防腐剂,包括甲基异噻唑啉酮和甲基氯异噻唑啉酮。由于并非所有的过敏原都准确地列在标签上,这可能会误导消费者。

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1
Baby wipes and nappy rash - what is the relationship? A review.婴儿湿巾与尿布疹——它们之间有何关系?一篇综述。
Australas J Dermatol. 2021 Nov;62(4):470-477. doi: 10.1111/ajd.13715. Epub 2021 Sep 15.
2
The BaSICS (Baby Skin Integrity Comparison Survey) study: A prospective experimental study using maternal observations to report the effect of baby wipes on the incidence of irritant diaper dermatitis in infants, from birth to eight weeks of age.BaSICS(婴儿皮肤完整性比较调查)研究:一项前瞻性实验研究,使用产妇观察报告婴儿湿巾对出生至 8 周龄婴儿刺激性尿布皮炎发生率的影响。
Pediatr Neonatol. 2021 Mar;62(2):138-145. doi: 10.1016/j.pedneo.2020.10.003. Epub 2020 Oct 23.
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Potential Allergens in Disposable Diaper Wipes, Topical Diaper Preparations, and Disposable Diapers: Under-recognized Etiology of Pediatric Perineal Dermatitis.一次性尿布湿巾、局部尿布制剂和一次性尿布中的潜在过敏原:小儿会阴部皮炎未被充分认识的病因
Dermatitis. 2016 May-Jun;27(3):110-8. doi: 10.1097/DER.0000000000000177.
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Skin care in the NICU patient: effects of wipes versus cloth and water on stratum corneum integrity.NICU 患儿的皮肤护理:湿巾与布和水对角质层完整性的影响。
Neonatology. 2009;96(4):226-34. doi: 10.1159/000215593. Epub 2009 Apr 29.
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What can be done to keep babies' skin healthy?可以采取什么措施来保持婴儿皮肤健康?
RCM Midwives. 2004 Jul;7(7):288-90.
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Effect on skin hydration of using baby wipes to clean the napkin area of newborn babies: assessor-blinded randomised controlled equivalence trial.使用婴儿湿巾清洁新生儿尿布区域对皮肤水合作用的影响:评估者盲法随机对照等效试验。
BMC Pediatr. 2012 Jun 1;12:59. doi: 10.1186/1471-2431-12-59.
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Disposable baby wipes: efficacy and skin mildness.
Dermatol Nurs. 2001 Apr;13(2):107-12, 117-8, 121.
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Six children with allergic contact dermatitis to methylisothiazolinone in wet wipes (baby wipes).六名儿童因湿巾(婴儿湿巾)中的甲基异噻唑啉酮而发生接触性过敏。
Pediatrics. 2014 Feb;133(2):e434-8. doi: 10.1542/peds.2013-1453. Epub 2014 Jan 13.
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Allergenic Ingredients in Personal Hygiene Wet Wipes.个人卫生湿巾中的变应原成分。
Dermatitis. 2017 Sep/Oct;28(5):317-322. doi: 10.1097/DER.0000000000000275.
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Cutaneous tolerance of baby wipes by infants with atopic dermatitis, and comparison of the mildness of baby wipe and water in infant skin.特应性皮炎婴儿对婴儿湿巾的皮肤耐受性以及婴儿湿巾与水对婴儿皮肤温和性的比较。
J Eur Acad Dermatol Venereol. 2001 Sep;15 Suppl 1:16-21. doi: 10.1046/j.0926-9959.2001.00004.x.

引用本文的文献

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Diaper dermatitis-a narrative review of clinical presentation, subtypes, and treatment.尿布皮炎:临床特征、亚型和治疗的叙述性综述。
Wien Med Wochenschr. 2024 Sep;174(11-12):246-256. doi: 10.1007/s10354-023-01024-6. Epub 2023 Oct 20.
2
Pediatricians' Knowledge, Attitudes, and Therapeutic Approaches Regarding Diaper Dermatitis: A Common Condition with Many Different Practices.儿科医生关于尿布皮炎的知识、态度及治疗方法:一种存在多种不同诊疗方式的常见病症
Clin Cosmet Investig Dermatol. 2023 Apr 5;16:901-910. doi: 10.2147/CCID.S405414. eCollection 2023.