Department of Biomedical Laboratory Science, School of Allied Health Sciences, University for Development Studies, Tamale, Ghana.
Am J Hum Biol. 2022 Apr;34(4):e23680. doi: 10.1002/ajhb.23680. Epub 2021 Sep 15.
Postpartum hematological and anthropometric assessment is a requirement for optimal maternal and child health. The study aimed to determine the relationship between the 2D:4D ratio and postpartum hematological and anthropometric variables in adult females.
The study was cross-sectional from December 2020 to April 2021 involving 272 postpartum adult females, aged between 18 and 36 years. The right (2D:4DR) and the left (2D:4DL) digit ratios were measured using computer-assisted analysis. Fasting venous samples were collected at a median (interquartile range) of 111 (44-210) days postpartum and analyzed for total testosterone (TT), estradiol, sex hormone-binding globulin, and complete blood count.
The mean ± standard deviation 2D:4DR and 2D:4DL were 0.94 ± 0.04 and 0.93 ± 0.04, respectively. As expected, the TT (r = -0.198, p = .015) and the free androgen index (FAI: r = -0.186, p = .019) were inversely correlated with the 2D:4DL while free testosterone (FT%: r = -0.157, p = .038) was inversely correlated with the 2D:4DR. The absolute basophile count (BASO: r = -0.124, p = .040) and the Platelet-lymphocyte ratio (PLR: r = -0.153, p = .016) were inversely correlated with the 2D:4DL and the 2D:4DR respectively. In addition, the mean cell volume was inversely correlated with the 2D:4DR (r = -0.139, p = .024) and the 2D:4DL (r = -0.122, p = .045). Moreover, the 2D:4DR was inversely correlated with height (r = -0.164, p = .007). Unexpectedly, the red blood cell count (RBC: r = 0.138, p = .025) was positively correlated with the 2D:4DR.
There are significant relationships between the 2D:4D ratio and postpartum female variables. These findings are useful preliminary reference data for postpartum research and subsequent 2D:4D ratio studies.
产后血液学和人体测量评估是母婴健康的基本要求。本研究旨在确定成年女性的 2D:4D 比值与产后血液学和人体测量学变量之间的关系。
这是一项 2020 年 12 月至 2021 年 4 月进行的横断面研究，共纳入 272 名产后成年女性，年龄在 18 至 36 岁之间。使用计算机辅助分析测量右（2D:4DR）和左（2D:4DL）指比率。产后中位数（四分位距）为 111 天（44-210 天）采集空腹静脉血样，分析总睾酮（TT）、雌二醇、性激素结合球蛋白和全血细胞计数。
平均±标准差的 2D:4DR 和 2D:4DL 分别为 0.94±0.04 和 0.93±0.04。如预期的那样，TT（r=-0.198，p=0.015）和游离雄激素指数（FAI：r=-0.186，p=0.019）与 2D:4DL 呈负相关，而游离睾酮（FT%：r=-0.157，p=0.038）与 2D:4DR 呈负相关。绝对嗜碱性粒细胞计数（BASO：r=-0.124，p=0.040）和血小板-淋巴细胞比值（PLR：r=-0.153，p=0.016）与 2D:4DL 和 2D:4DR 呈负相关。此外，平均细胞体积与 2D:4DR（r=-0.139，p=0.024）和 2D:4DL（r=-0.122，p=0.045）呈负相关。此外，2D:4DR 与身高呈负相关（r=-0.164，p=0.007）。出乎意料的是，红细胞计数（RBC：r=0.138，p=0.025）与 2D:4DR 呈正相关。
2D:4D 比值与产后女性变量之间存在显著关系。这些发现为产后研究和随后的 2D:4D 比值研究提供了有用的初步参考数据。
