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心力衰竭中的钾缺乏及其与利尿剂长期治疗的关系:文献综述

Potassium depletion in heart failure and its relation to long-term treatment with diuretics: a review of the literature.

作者信息

Morgan D B, Burkinshaw L, Davidson C

出版信息

Postgrad Med J. 1978 Feb;54(628):72-9. doi: 10.1136/pgmj.54.628.72.

Abstract

There have been many studies which suggest that patients with heart failure were potassium depleted. This depletion has been attributed to the use of potent diuretics, and these are now given with either potassium supplements or potassium-retaining diuretics. A detailed examination of the studies suggests that the reported decrease in body potassium compared with the results in healthy persons is not due to the diuretics. It can be partly explained by a failure to match patients and controls in terms of age, and the remaining difference can be explained by muscle wasting. There is therefore no evidence of a potassium depletion in these patients with heart failure.

摘要

有许多研究表明,心力衰竭患者存在钾缺乏。这种缺乏归因于强效利尿剂的使用,现在使用这些利尿剂时会同时给予钾补充剂或保钾利尿剂。对这些研究的详细检查表明,与健康人相比,报告的身体钾含量下降并非由于利尿剂。部分原因可以解释为在年龄方面未能使患者和对照组相匹配,其余差异可以用肌肉萎缩来解释。因此,没有证据表明这些心力衰竭患者存在钾缺乏。

相似文献

2
Potassium replacement: supplements or potassium-sparing diuretics?
Drugs. 1979 Sep;18(3):218-25. doi: 10.2165/00003495-197918030-00004.

本文引用的文献

1
The exchangeable potassium content of normal women.正常女性的可交换钾含量。
J Clin Invest. 1952 Apr;31(4):367-9. doi: 10.1172/JCI102617.
2
The distribution of sodium and potassium in man.人体中钠和钾的分布。
J Clin Invest. 1952 Feb;31(2):197-9. doi: 10.1172/JCI102591.
10
Exchangeable potassium in wasting, amyotrophy, heart-disease, and cirrhosis of the liver.
Lancet. 1961 Apr 1;1(7179):681-7. doi: 10.1016/s0140-6736(61)91719-6.

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