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[年轻成年哮喘患者群体中对腐败食酪螨和嗜卷书虱的过敏反应]

[Allergy to Thyrophagus putrescentiae and Lepidoglyphus destructor in a population of young asthmatic adults].

作者信息

Hardel P J, de Lajudie J P, Portal B, Ville G, Guilloux L, D'Athis P

机构信息

Hôpitaux des Armées.

出版信息

Allerg Immunol (Paris). 1987 Dec;19(10):399-402, 404-5.

PMID:3453125
Abstract

In the present work a study has been made of the prevalence of allergy to two storage mites, Tyrophagus putrescentiae and Lepidoglyphus destructor in a population of 105 young adults in the east of France. Combination of skin tests and specific IgE measurements shows that 43.10% of the subjects were sensitive to Tyrophagus and 44.95% to Lepidoglyphus. Interpretation of skin tests remains uncertain, particularly concerning the source of the allergen used and it is most often also necessary to measure the specific serum IgE. As in many studies, most sensitization was found amongst farmers. In contrast, no difference was seen between rural and city dwellers, subjects who were in contact with small animals and those in contact with food for livestock if they were not farmers, not between declared asthmatics who lived in a humid place and those who lived in an environment that was drier. Certainly these mites appeared in the present study to be much more ubiquitous than supposed previously and the fact that they seemed to be carriers of allergens and antigens that were different from those of Dermatophagoides raises the question as to whether the need for hyposensitization treatment for them has been under-estimated.

摘要

在本研究中,对法国东部105名年轻成年人中对两种仓储螨即腐食酪螨和害嗜鳞螨过敏的患病率进行了调查。皮肤试验和特异性IgE测量结果显示,43.10%的受试者对腐食酪螨敏感,44.95%对害嗜鳞螨敏感。皮肤试验的结果仍不确定,尤其是关于所用过敏原的来源,而且通常还需要检测特异性血清IgE。与许多研究一样,大多数致敏情况发生在农民中。相比之下,农村居民和城市居民之间、接触小动物的人和接触家畜饲料但不是农民的人之间、居住在潮湿环境中的确诊哮喘患者和居住在干燥环境中的患者之间均未发现差异。当然,在本研究中这些螨似乎比以前认为的更为普遍,而且它们似乎是不同于粉尘螨的过敏原和抗原的携带者,这就引发了一个问题,即对它们进行减敏治疗的必要性是否被低估了。

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