Harrabi S, Loiseau P, Dehenry J, Harrabi S
Laboratoire de Biologie P. Loiseau et J. Dehenry, Sens.
Allerg Immunol (Paris). 1987 Oct;19(8):330, 332.
We studied degranulation of human basophils (HBDT), lymphoblast transformation and leucocyte migration in 8 cases of patients who were sensitive to penicillin (type 1 hypersensitization of the Gell and Coombes classification). The HBDT was negative in 7 of the cases, whilst the lymphoblast transformation and leucocyte migration tests were positive in 6 cases and negative in 2. These latter tests are more efficient than HBDT in the detection of human sensitization to penicillin.